Protein Alignment CG11841 and PRSS48

DIOPT Version :10

• Sequence 1: NP_651661.1
• Gene: CG11841 / 43430
• FlyBaseID: FBgn0039628
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_001340540.1
• Gene: PRSS48 / 345062
• HGNCID: 24635
• Length: 346
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 80/282 - (28%)
• Similarity: 123/282 - (43%)
• Gaps: 68/282 - (24%)

  Fly    66 HGSRPLIVDGTPAEPKEFPFAARLGHRKTNNEIKWFCGGTLISNRLVLTAAHCF------FSEHG 124
            :.||  :|.|..|....:|:...| |...|    :.|||:|:|.||:||||||.      ||
Human    24 YSSR--VVGGQDAAAGRWPWQVSL-HFDHN----FICGGSLVSERLILTAAHCIQPTWTTFS--- 78

  Fly   125 EVNVVRLGELEFDTDTDDAEPEDFGVLALKAHPGFENPQLYNDIGIVQLDREVKFNRYKHPACLP 189
              ..|.||.:   |..|..:...:.|..:..||.:::...  |:.:::|..:|.|.....|.|||
Human    79 --YTVWLGSI---TVGDSRKRVKYYVSKIVIHPKYQDTTA--DVALLKLSSQVTFTSAILPICLP 136

  Fly   190 FDDGEQHESFIAI-------GWGQ-KKFAQKESKKLLKVQLQGYKDRCVSSVDANDELPN----- 241
            ....:     :||       |||: |:.:.::....|:.......||     .|.::|.|
Human   137 SVTKQ-----LAIPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDR-----QACEQLYNPIGIF 191

  Fly   242 --GYEP---KSQLCIGSRDN-KDTCNGDSGGPVLAYHKDLACMYHV------MGITSAGITCSTP 294
              ..||   :.::|.|...| ||:|.||||||       |:|  |:      .|:.|.|:.|. .
Human   192 LPALEPVIKEDKICAGDTQNMKDSCKGDSGGP-------LSC--HIDGVWIQTGVVSWGLECG-K 246

  Fly   295 DIPSAYTRVHYFLNWIKGELAK 316
            .:|..||.|.|:..||...:::
Human   247 SLPGVYTNVIYYQKWINATISR 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11841	NP_651661.1	Tryp_SPc	72..311	CDD:238113	77/269 (29%)
PRSS48	NP_001340540.1	Tryp_SPc	28..265	CDD:238113	78/271 (29%)