Protein Alignment CG11841 and TMPRSS11E

DIOPT Version :10

• Sequence 1: NP_651661.1
• Gene: CG11841 / 43430
• FlyBaseID: FBgn0039628
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_054777.2
• Gene: TMPRSS11E / 28983
• HGNCID: 24465
• Length: 423
• Species: Homo sapiens
• Alignment Length: 335
• Identity: 93/335 - (27%)
• Similarity: 140/335 - (41%)
• Gaps: 77/335 - (22%)

  Fly     4 QSLELILLLVFSLSSSLVQGQNP---DPFAQLACTKFKQIVFEERVAISFFFTDAPITYETVDSC 65
            ::::.|:.||  |...|.....|   ||.:    .|.|:|...|        ||:.:.:     |
Human   132 ETVDKIVQLV--LHEKLQDAVGPPKVDPHS----VKIKKINKTE--------TDSYLNH-----C 177

  Fly    66 HGSRP--------LIVDGTPAEPKEFPFAARL----GHRKTNNEIKWFCGGTLISNRLVLTAAHC 118
            .|:|.        .||.||..|..|:|:.|.|    .||         ||.|||:...:::||||
Human   178 CGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHR---------CGATLINATWLVSAAHC 233

  Fly   119 FFSEHGEVNVVRLGELEFDTDTDDAEPEDFGVLALKAHPGFENPQLYNDIGIVQLDREVKFNRYK 183
            |.:..   |..| ....|......::.:. |:..:..|..:::|....||.:.:|...|.:....
Human   234 FTTYK---NPAR-WTASFGVTIKPSKMKR-GLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAV 293

  Fly   184 HPACLP-----FDDGEQHESFIAIGWGQKKFAQKESKKLLKVQLQGYKDRCVSSVDA---NDELP 240
            |..|||     |..|   :.....|:|..|........|.:.|        |:.:||   |:  |
Human   294 HRVCLPDASYEFQPG---DVMFVTGFGALKNDGYSQNHLRQAQ--------VTLIDATTCNE--P 345

  Fly   241 NGYE----PKSQLCIGSRDNK-DTCNGDSGGPVLAYHKDLACMYHVMGITSAGITCSTPDIPSAY 300
            ..|.    |: .||.||.:.| |.|.||||||:::  .|...::::.||.|.|..|:.|:.|..|
Human   346 QAYNDAITPR-MLCAGSLEGKTDACQGDSGGPLVS--SDARDIWYLAGIVSWGDECAKPNKPGVY 407

  Fly   301 TRVHYFLNWI 310
            |||....:||
Human   408 TRVTALRDWI 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11841	NP_651661.1	Tryp_SPc	72..311	CDD:238113	76/256 (30%)
TMPRSS11E	NP_054777.2	SEA	51..147	CDD:460188	4/16 (25%)
		Tryp_SPc	192..420	CDD:238113	76/256 (30%)