Protein Alignment CG11841 and F12

DIOPT Version :10

• Sequence 1: NP_651661.1
• Gene: CG11841 / 43430
• FlyBaseID: FBgn0039628
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_000496.2
• Gene: F12 / 2161
• HGNCID: 3530
• Length: 615
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 72/262 - (27%)
• Similarity: 105/262 - (40%)
• Gaps: 46/262 - (17%)

  Fly    72 IVDGTPAEPKEFPFAARL--GHRKTNNEIKWFCGGTLISNRLVLTAAHCFFSEHG--EVNVVRLG 132
            :|.|..|.....|:.|.|  ||.        ||.|:||:...|||||||......  ::.|| ||
Human   373 VVGGLVALRGAHPYIAALYWGHS--------FCAGSLIAPCWVLTAAHCLQDRPAPEDLTVV-LG 428

  Fly   133 ELEFDTDTDDAEP-EDFGVLALKAHPGFENPQLYNDIGIVQLDREVK-----FNRYKHPACLPFD 191
            :   :......|| :...|.:.:.|..|......:|:.:::|..:..     .:.|..|.|||..
Human   429 Q---ERRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVCLPSG 490

  Fly   192 DGEQHESFI--AIGWGQK--------KFAQKESKKLLKVQLQGYKDRC-VSSVDANDELPNGYEP 245
            .....|:.:  ..|||.:        .|.|:.....|.:      :|| ...|..:..||
Human   491 AARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSL------ERCSAPDVHGSSILP----- 544

  Fly   246 KSQLCIGSRD-NKDTCNGDSGGPVLAYHKDLACMYHVMGITSAGITCSTPDIPSAYTRVHYFLNW 309
             ..||.|..: ..|.|.||||||::...:.......:.||.|.|..|...:.|..||.|.|:|.|
Human   545 -GMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYLAW 608

  Fly   310 IK 311
            |:
Human   609 IR 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11841	NP_651661.1	Tryp_SPc	72..311	CDD:238113	71/260 (27%)
F12	NP_000496.2	FN2	41..88	CDD:128373
		EGF_CA	96..131	CDD:238011
		FN1	133..173	CDD:238018
		EGF	178..206	CDD:394967
		Kringle	217..295	CDD:395005
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	298..359
		Tryp_SPc	373..612	CDD:238113	72/262 (27%)