DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11841 and Plau

DIOPT Version :9

Sequence 1:	NP_651661.1	Gene:	CG11841 / 43430	FlyBaseID:	FBgn0039628	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_032899.1	Gene:	Plau / 18792	MGIID:	97611	Length:	433	Species:	Mus musculus

Alignment Length:	326	Identity:	87/326 - (26%)
Similarity:	145/326 - (44%)	Gaps:	53/326 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 QNPDP------FAQLACTKFKQIVFEERVAISFFFTDAPITYETVD----SCHGSRPL-----IV 73
            :|||.      :.|:...:|.|.......::|    ..|.:  :||    .| |.:.|     ||
Mouse   124 RNPDNQKRPWCYVQIGLRQFVQECMVHDCSLS----KKPSS--SVDQQGFQC-GQKALRPRFKIV 181

  Fly    74 DGTPAEPKEFP-FAARLGHRKTNNEIKWFCGGTLISNRLVLTAAHCFFSEHGEVN-VVRLGELEF 136
            .|...|.:..| |||.....|..:...:.|||:|||...|.:|||||.....:.| ||.||:.:
Mouse   182 GGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVVYLGQSK- 245

  Fly   137 DTDTDDAEPEDFGVLALKAHPGFENPQL--YNDIGIVQLDRE----VKFNRYKHPACLP--FDDG 193
            ::..:..|.: |.|..|..|..:....|  :|||.::::...    .:.:|.....|||  |.|.
Mouse   246 ESSYNPGEMK-FEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQTICLPPRFTDA 309

  Fly   194 EQHESFIAIGWGQKK---FAQKESKKLLKVQLQGYKDRCVSSVDANDELPNGYEPK---SQLCIG 252
            .........|:|::.   :...::.|:..|:|..: ::|:.        |:.|..:   ..||..
Mouse   310 PFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSH-EQCMQ--------PHYYGSEINYKMLCAA 365

  Fly   253 SRDNK-DTCNGDSGGPVLAYHKDLACMYHVMGITSAGITCSTPDIPSAYTRVHYFLNWIKGELAK 316
            ..:.| |:|.||||||::.   ::.....:.||.|.|..|:..:.|..||||.:||:||:..:.:
Mouse   366 DPEWKTDSCKGDSGGPLIC---NIEGRPTLSGIVSWGRGCAEKNKPGVYTRVSHFLDWIQSHIGE 427

  Fly   317 Q 317
            :
Mouse   428 E 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11841	NP_651661.1	Tryp_SPc	72..311	CDD:238113	73/255 (29%)
CG11841	NP_651661.1	Tryp_SPc	72..310	CDD:214473	72/254 (28%)
Plau	NP_032899.1	Binds urokinase plasminogen activator surface receptor. /evidence=ECO:0000250	35..58
		Kringle	71..152	CDD:333799	6/27 (22%)
		Connecting peptide	153..179		7/32 (22%)
		Tryp_SPc	180..424	CDD:238113	74/257 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4773
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050