DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11841 and Plat

DIOPT Version :9

Sequence 1:	NP_651661.1	Gene:	CG11841 / 43430	FlyBaseID:	FBgn0039628	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_032898.2	Gene:	Plat / 18791	MGIID:	97610	Length:	559	Species:	Mus musculus

Alignment Length:	329	Identity:	90/329 - (27%)
Similarity:	136/329 - (41%)	Gaps:	83/329 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 QNPDPFAQLACTKFKQIVFEERVAISFFFTDAPITYETVD-----SC---HGSRP--LIVDGTPA 78
            :|||..|:..|...|               |..:|:|..|     :|   ...||  .|..|...
Mouse   266 RNPDGDARPWCHVMK---------------DRKLTWEYCDMSPCSTCGLRQYKRPQFRIKGGLYT 315

  Fly    79 EPKEFPFAARL--GHRKTNNEIKWFCGGTLISNRLVLTAAHCFFS----EHGEVNVVRL-----G 132
            :....|:.|.:  .::::..| ::.|||.|||:..||:|||||..    .|.:|.:.|.     |
Mouse   316 DITSHPWQAAIFVKNKRSPGE-RFLCGGVLISSCWVLSAAHCFLERFPPNHLKVVLGRTYRVVPG 379

  Fly   133 ELEFDTDTDDAEPEDFGVLALKAHPGFENPQLYNDIGIVQLDREVKFNRYKH----PACLP---- 189
            |          |.:.|.:.....|..|::....|||.::||..:.|....:.    .||||
Mouse   380 E----------EEQTFEIEKYIVHEEFDDDTYDNDIALLQLRSQSKQCAQESSSVGTACLPDPNL 434

  Fly   190 -FDDGEQHESFIAIGWGQKKFAQK-ESKKLLKVQLQGY-KDRCVSSVDANDELPNGYEPKSQLCI 251
             ..|..:.|   ..|:|:.:.:.. .|.:|.:..::.| ..||.|....|..:.|     :.||.
Mouse   435 QLPDWTECE---LSGYGKHEASSPFFSDRLKEAHVRLYPSSRCTSQHLFNKTVTN-----NMLCA 491

  Fly   252 ------GSRDNKDTCNGDSGGPVLAYHKDLACMYH----VMGITSAGITCSTPDIPSAYTRVHYF 306
                  |::|..|.|.||||||       |.||.:    :.||.|.|:.|...|:|..||:|..:
Mouse   492 GDTRSGGNQDLHDACQGDSGGP-------LVCMINKQMTLTGIISWGLGCGQKDVPGVYTKVTNY 549

  Fly   307 LNWI 310
            |:||
Mouse   550 LDWI 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11841	NP_651661.1	Tryp_SPc	72..311	CDD:238113	77/271 (28%)
CG11841	NP_651661.1	Tryp_SPc	72..310	CDD:214473	75/269 (28%)
Plat	NP_032898.2	FN1	38..80	CDD:214494
		Important for binding to annexin A2. /evidence=ECO:0000250	39..49
		EGF	83..115	CDD:394967
		Kringle	124..205	CDD:395005
		KR	210..295	CDD:238056	10/43 (23%)
		Tryp_SPc	311..556	CDD:238113	76/269 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4773
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050