Protein Alignment CG11841 and CFD

DIOPT Version :10

• Sequence 1: NP_651661.1
• Gene: CG11841 / 43430
• FlyBaseID: FBgn0039628
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_001304264.1
• Gene: CFD / 1675
• HGNCID: 2771
• Length: 260
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 76/289 - (26%)
• Similarity: 115/289 - (39%)
• Gaps: 50/289 - (17%)

  Fly    44 ERVAISFFFTDAPITYETVDSCHGSRPLIVDGTPAEPKEFPFAARL----GHRKTNNEIKWFCGG 104
            ||:|:......|....|........|..|:.|..||....|:.|.:    .|         .|||
Human     5 ERLAVLVLLGAAACGEEAWAWAAPPRGRILGGREAEAHARPYMASVQLNGAH---------LCGG 60

  Fly   105 TLISNRLVLTAAHCF-FSEHGEVNVVRLGELEFDTDTDDAEPED----FGVLALKAHPGFENPQL 164
            .|::.:.||:||||. .:..|:|.|: ||....      ::||.    :.||....||..:...:
Human    61 VLVAEQWVLSAAHCLEDAADGKVQVL-LGAHSL------SQPEPSKRLYDVLRAVPHPDSQPDTI 118

  Fly   165 YNDIGIVQLDREVKFNRYKHPACLPFDDGEQHESFIA-------IGWGQKKFAQKESKKLLKVQL 222
            .:|:.::||..:........|  ||:   ::.:..:|       .|||....|.:....|..|.|
Human   119 DHDLLLLQLSEKATLGPAVRP--LPW---QRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLL 178

  Fly   223 QGYKDRCVSSVDANDELPNGYEPKSQLCIGSRDNKDTCNGDSGGPVLAYHKDLACMYHVMG-ITS 286
            . ..||...:...:.:   |...:..:|..| :.:|:|.||||||       |.|...:.| :||
Human   179 P-VLDRATCNRRTHHD---GAITERLMCAES-NRRDSCKGDSGGP-------LVCGGVLEGVVTS 231

  Fly   287 AGITCSTPDIPSAYTRVHYFLNWIKGELA 315
            ....|.....|..||||..:..||...||
Human   232 GSRVCGNRKKPGIYTRVASYAAWIDSVLA 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11841	NP_651661.1	Tryp_SPc	72..311	CDD:238113	67/255 (26%)
CFD	NP_001304264.1	Tryp_SPc	33..258	CDD:238113	68/257 (26%)