Protein Alignment CG11841 and KLK11

DIOPT Version :10

• Sequence 1: NP_651661.1
• Gene: CG11841 / 43430
• FlyBaseID: FBgn0039628
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 344
• Identity: 78/344 - (22%)
• Similarity: 120/344 - (34%)
• Gaps: 107/344 - (31%)

  Fly     3 MQSLELILLLVFSLSSSLVQGQNPDPFAQLACTKFKQIVFEERVAISFFFTDAPITYETVDSCHG 67
            :|::.::.|::.:|::.||.|:.
Human    30 LQAMRILQLILLALATGLVGGET------------------------------------------ 52

  Fly    68 SRPLIVDGTPAEPKEFPFAARLGHRKTNNEIKWFCGGTLISNRLVLTAAHC-------------- 118
               .|:.|...:|...|:.|.| ..||    :..||.|||:.|.:||||||
Human    53 ---RIIKGFECKPHSQPWQAAL-FEKT----RLLCGATLIAPRWLLTAAHCLKPWVSLTSPTHVS 109

  Fly   119 -------FFSEHGEVNVVRLG----ELEFDTDTDDAEPEDFGVLALKAHPGFE----NPQLYNDI 168
                   :...|....:|.||    :.|...:......|.|      .||||.    |....|||
Human   110 PDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESF------PHPGFNNSLPNKDHRNDI 168

  Fly   169 GIVQLDREVKFNRYKHPACLPFDDGEQHESFIAIGWGQKKFAQKESKKLLKVQLQGYKDRCVS-S 232
            .:|::...|.......|..|.........|.:..|||.....|......|         ||.: :
Human   169 MLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTL---------RCANIT 224

  Fly   233 VDANDELPNGYE---PKSQLCIGSRD-NKDTCNGDSGGPVLAYHKDLACMYHVMGITSAG-ITCS 292
            :..:.:..|.|.   ..:.:|...:: .||:|.||||||       |.|...:.||.|.| ..|:
Human   225 IIEHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGP-------LVCNQSLQGIISWGQDPCA 282

  Fly   293 TPDIPSAYTRVHYFLNWIK 311
            ....|..||:|..:::||:
Human   283 ITRKPGVYTKVCKYVDWIQ 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11841	NP_651661.1	Tryp_SPc	72..311	CDD:238113	71/273 (26%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	70/273 (26%)