Protein Alignment MOV10 and Mov10

DIOPT Version :10

• Sequence 1: NP_066014.1
• Gene: MOV10 / 4343
• HGNCID: 7200
• Length: 1003
• Species: Homo sapiens
• Sequence 2: NP_032645.2
• Gene: Mov10 / 17454
• MGIID: 97054
• Length: 1004
• Species: Mus musculus
• Alignment Length: 1004
• Identity: 915/1004 - (91%)
• Similarity: 954/1004 - (95%)
• Gaps: 1/1004 - (0%)

Human     1 MPSKFSCRQLREAGQCFESFLVVRGLDMETDRERLRTIYNRDFKISFGTPAPGFSSMLYGMKIAN 65
            ||||||||:|||.||.|||||..||||:||||||||||||.|||.|:||||||||||||||||||
Mouse     1 MPSKFSCRKLRETGQRFESFLAERGLDLETDRERLRTIYNHDFKPSYGTPAPGFSSMLYGMKIAN 65

Human    66 LAYVTKTRVRFFRLDRWADVRFPEKRRMKLGSDISKHHKSLLAKIFYDRAEYLHGKHGVDVEVQG 130
            ||:|||||||||:|||||||:.|||||:|.||:|||.|:||||:||:||||||||||||||||||
Mouse    66 LAFVTKTRVRFFKLDRWADVQLPEKRRIKPGSNISKQHRSLLARIFHDRAEYLHGKHGVDVEVQG 130

Human   131 PHEARDGQLLIRLDLNRKEVLTLRLRNGGTQSVTLTHLFPLCRTPQFAFYNEDQELPCPLGPGEC 195
            |||||||||||.|||||||||||||||||::.||||||||||.||||.||:.:|:|||||||||.
Mouse   131 PHEARDGQLLIHLDLNRKEVLTLRLRNGGSKPVTLTHLFPLCWTPQFVFYHGEQDLPCPLGPGES 195

Human   196 YELHVHCKTSFVGYFPATVLWELLGPGESGSEGAGTFYIARFLAAVAHSPLAAQLKPMTPFKR-T 259
            ||||::||||.|||||||||||||||||||:|||.||||||||||||||||||||||.||||| .
Mouse   196 YELHIYCKTSIVGYFPATVLWELLGPGESGAEGAETFYIARFLAAVAHSPLAAQLKPTTPFKRPP 260

Human   260 RITGNPVVTNRIEEGERPDRAKGYDLELSMALGTYYPPPRLRQLLPMLLQGTSIFTAPKEIAEIK 324
            |:|.|.|:||||||||||||||||:||||:||||||||..||||||.||||.||||||||:||||
Mouse   261 RLTRNSVLTNRIEEGERPDRAKGYELELSLALGTYYPPILLRQLLPTLLQGPSIFTAPKEVAEIK 325

Human   325 AQLETALKWRNYEVKLRLLLHLEELQMEHDIRHYDLESVPMTWDPVDQNPRLLTLEVPGVTESRP 389
            |||||.||.|||||||||||||||||||||||||||:|||||||||||||||||||||||.||||
Mouse   326 AQLETTLKSRNYEVKLRLLLHLEELQMEHDIRHYDLDSVPMTWDPVDQNPRLLTLEVPGVAESRP 390

Human   390 SVLRGDHLFALLSSETHQEDPITYKGFVHKVELDRVKLSFSMSLLSRFVDGLTFKVNFTFNRQPL 454
            ||||||||||||||||.|:||:|||||||||||||||||||.|||||||||||||||||||||||
Mouse   391 SVLRGDHLFALLSSETQQDDPVTYKGFVHKVELDRVKLSFSTSLLSRFVDGLTFKVNFTFNRQPL 455

Human   455 RVQHRALELTGRWLLWPMLFPVAPRDVPLLPSDVKLKLYDRSLESNPEQLQAMRHIVTGTTRPAP 519
            |||||||||||||:|||||||||.|.|.|||||||.|||||||||||||||||:|||.|||||||
Mouse   456 RVQHRALELTGRWVLWPMLFPVASRGVSLLPSDVKFKLYDRSLESNPEQLQAMKHIVRGTTRPAP 520

Human   520 YIIFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAPSRD 584
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   521 YIIFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAPSRD 585

Human   585 IRMVPEDIKPCCNWDAKKGEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGH 649
            |||||||||.||||||||||||:||||.||:|||||||||||.||||||||||||||||||||||
Mouse   586 IRMVPEDIKTCCNWDAKKGEYVYPAKKHLQQYRVLITTLITASRLVSAQFPIDHFTHIFIDEAGH 650

Human   650 CMEPESLVAIAGLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYK 714
            ||||||||||||||:|||||:||||||||||||||||||||||..|||||||||||||.||||||
Mouse   651 CMEPESLVAIAGLMDVKETGNPGGQLVLAGDPRQLGPVLRSPLALKHGLGYSLLERLLAYNSLYK 715

Human   715 KGPDGYDPQFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFH 779
            |||:|||||||||||||||||||||||||||||:||||||||||||||||||.|||:||||||||
Mouse   716 KGPNGYDPQFITKLLRNYRSHPTILDIPNQLYYDGELQACADVVDRERFCRWEGLPQQGFPIIFH 780

Human   780 GVMGKDEREGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKIRYCI 844
            |||||||||||||||||||||||||||||.||||||||||||||||:||||||||||||||||||
Mouse   781 GVMGKDEREGNSPSFFNPEEAATVTSYLKQLLAPSSKKGKARLSPRNVGVISPYRKQVEKIRYCI 845

Human   845 TKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLKNPKRFNVAV 909
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   846 TKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLKNPKRFNVAV 910

Human   910 TRAKALLIIVGNPLLLGHDPDWKVFLEFCKENGGYTGCPFPAKLDLQQGQNLLQGLSKLSPSTSG 974
            ||||||||:||||||||||||||.||||||||||||||||||||||||||:||||||||||||||
Mouse   911 TRAKALLIVVGNPLLLGHDPDWKTFLEFCKENGGYTGCPFPAKLDLQQGQDLLQGLSKLSPSTSG 975

Human   975 PHSHDYLPQEREGEGGLSLQVEPEWRNEL 1003
            |..|..|||||||||||.|||||||||||
Mouse   976 PRRHQNLPQEREGEGGLPLQVEPEWRNEL 1004

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MOV10	NP_066014.1	DEXXQc_Helz-like	498..733	CDD:350796	221/234 (94%)
		DEAG box	645..648		2/2 (100%)
		SF1_C_Upf1	734..939	CDD:350195	197/204 (97%)
		Interaction with AGO2 and APOBEC3G. /evidence=ECO:0000269|PubMed:22791714	921..965		41/43 (95%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	966..1003		31/36 (86%)
Mov10	NP_032645.2	DEXXQc_Helz-like	499..734	CDD:350796	221/234 (94%)
		DEAG box	646..649		2/2 (100%)
		SF1_C_Upf1	735..940	CDD:350195	197/204 (97%)
		Interaction with AGO2 and APOBEC3G. /evidence=ECO:0000250	922..966		41/43 (95%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	966..1004		32/37 (86%)