DRSC/TRiP Functional Genomics Resources

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Protein Alignment MOV10 and rrf-3

DIOPT Version :10

Sequence 1:NP_066014.1 Gene:MOV10 / 4343 HGNCID:7200 Length:1003 Species:Homo sapiens
Sequence 2:NP_495713.2 Gene:rrf-3 / 174315 WormBaseID:WBGene00004510 Length:1765 Species:Caenorhabditis elegans


Alignment Length:140 Identity:33/140 - (23%)
Similarity:54/140 - (38%) Gaps:52/140 - (37%)


- Green bases have known domain annotations that are detailed below.


Human   101 LTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLP-----DQREVNERQARELAEKYGIP-Y 159
            |.:.|:...|:|..|.|.||               :||     ||| ||..|.      ..:| :
 Worm    52 LRNIQTLFAVKNLRSILGAN---------------NLPLNTSRDQR-VNPNQV------VRVPIH 94

Human   160 FETSAATG---QNVEKSV--ETLLDLIMKRM-------EKCVEKTQVPDTVNGGNSGKLD-GEK- 210
            ...|..||   :::|.::  :.:|..:...:       ||..|..::||      ..|:: |:| 
 Worm    95 CSCSNGTGVSNRDIEYTIKKDDILSFVATEIFGGLVTYEKISEVNKIPD------PNKIEIGQKF 153

Human   211 --PAEKKCAC 218
              |.  .|:|
 Worm   154 WIPL--PCSC 161

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MOV10NP_066014.1 DEXXQc_Helz-like 498..733 CDD:350796
DEAG box 645..648
SF1_C_Upf1 734..939 CDD:350195
Interaction with AGO2 and APOBEC3G. /evidence=ECO:0000269|PubMed:22791714 921..965
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 966..1003
rrf-3NP_495713.2 RdRP 691..1267 CDD:461574
Blue background indicates that the domain is not in the aligned region.

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