Protein Alignment MOV10 and rrf-2

DIOPT Version :10

• Sequence 1: NP_066014.1
• Gene: MOV10 / 4343
• HGNCID: 7200
• Length: 1003
• Species: Homo sapiens
• Sequence 2: NP_493057.1
• Gene: rrf-2 / 173092
• WormBaseID: WBGene00004509
• Length: 1579
• Species: Caenorhabditis elegans
• Alignment Length: 195
• Identity: 32/195 - (16%)
• Similarity: 61/195 - (31%)
• Gaps: 70/195 - (35%)

Human    28 RYTDNKFNPKFITTVGIDF-----REKRVVYDTQGADGASGKAFKVH------------------ 69
            |....:|....:.::.:||     |.:|.|    ...|...|.|..|
 Worm    48 RVLSKRFRETEVRSLDLDFSGIYSRRRRKV----EVVGIIEKVFNQHKGSEIHRFVLLLNHIGVE 108

Human    70 --LQLW-DTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLI 131
              :..| :|...:..:.|...|.:......:..|.::.:|.        |:....:|
 Worm   109 DKIISWTNTCFDKNIKELVLDFSKSRKVMAIPIDFSAVESL--------QVLKLRWC-------- 157

Human   132 GNKADLPDQREVNERQARELAEKYGIPYFET-SAATGQNVEKSVETL---------LDLIMKRME 186
              |.::||            :...|:...:| |....|.:.|:::.:         |:||..||:
 Worm   158 --KFEIPD------------SSPKGLKLLKTLSLMRTQVMVKTIDAIFNNCIHLESLELIECRMD 208

Human   187  186
             Worm   209  208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MOV10	NP_066014.1	DEXXQc_Helz-like	498..733	CDD:350796
		DEAG box	645..648
		SF1_C_Upf1	734..939	CDD:350195
		Interaction with AGO2 and APOBEC3G. /evidence=ECO:0000269|PubMed:22791714	921..965
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	966..1003
rrf-2	NP_493057.1	RdRP	462..1075	CDD:461574