DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11837 and DIM1

DIOPT Version :9

Sequence 1:	NP_651660.1	Gene:	CG11837 / 43429	FlyBaseID:	FBgn0039627	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_015057.1	Gene:	DIM1 / 855862	SGDID:	S000006187	Length:	318	Species:	Saccharomyces cerevisiae

Alignment Length:	319	Identity:	177/319 - (55%)
Similarity:	237/319 - (74%)	Gaps:	14/319 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPKVTKEKKSRIHNDVQKQG-------IVFNKDFGQHILKNPLVITTMLEKAALRATDVVLEIGP 58
            |.|..|:|.|...:..|...       ..||.|.||||||||||...:::||.:|.:|||||:||
Yeast     1 MGKAAKKKYSGATSSKQVSAEKHLSSVFKFNTDLGQHILKNPLVAQGIVDKAQIRPSDVVLEVGP 65

  Fly    59 GTGNMTVRMLERAKKVIACEIDTRLAAELQKRVQATPLQPKLQVLIGDFLKAELPFFDLCIANVP 123
            ||||:|||:||:||.|:|.|:|.|:||||.|||:.||::.||::::|||:|.|||:||:||:|.|
Yeast    66 GTGNLTVRILEQAKNVVAVEMDPRMAAELTKRVRGTPVEKKLEIMLGDFMKTELPYFDICISNTP 130

  Fly   124 YQISSPLIFKLLLHRPLFRCAVLMFQREFAERLVAKPGDKLYCRLSINTQLLARVDMLMKVGKNN 188
            |||||||:|||:......|.::||||||||.||:|:|||.||||||.|.|:.|.|..:|||||||
Yeast   131 YQISSPLVFKLINQPRPPRVSILMFQREFALRLLARPGDSLYCRLSANVQMWANVTHIMKVGKNN 195

  Fly   189 FRPPPKVESSVVRLEPKNPPPPVNFTEWDGLTRIAFLRKNKTLAATFKVTSVLEMLEKNYKLYRS 253
            |||||:|||||||||.|||.|.|::.|||||.||.|:|||:|::|.||.|:|:::||||||.:.:
Yeast   196 FRPPPQVESSVVRLEIKNPRPQVDYNEWDGLLRIVFVRKNRTISAGFKSTTVMDILEKNYKTFLA 260

  Fly   254 LRNEPIEDDFK------MQDKVISILEEQDMAAKRARSMDIDDFMRLLLAFNSAGIHFN 306
            :.||.: ||.|      :::|:.::|:|.|:..|||...|.:||:|||.||:..||||:
Yeast   261 MNNEMV-DDTKGSMHDVVKEKIDTVLKETDLGDKRAGKCDQNDFLRLLYAFHQVGIHFS 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11837	NP_651660.1	PTZ00338	16..305	CDD:240367	170/301 (56%)
DIM1	NP_015057.1	AdoMet_MTases	28..317	CDD:418430	169/289 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345808
Domainoid	1	1.000	311	1.000	Domainoid score	I204
eggNOG	1	0.900	-	-		E1_COG0030
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7047
Inparanoid	1	1.050	351	1.000	Inparanoid score	I394
Isobase	1	0.950	-	0	Normalized mean entropy	S279
OMA	1	1.010	-	-		QHG53890
OrthoFinder	1	1.000	-	-		FOG0002924
OrthoInspector	1	1.000	-	-		oto99973
orthoMCL	1	0.900	-	-		OOG6_100569
Panther	1	1.100	-	-	LDO	PTHR11727
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R317
SonicParanoid	1	1.000	-	-		X3272
TreeFam	1	0.960	-	-
	16	15.740