DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11837 and Dimt1

DIOPT Version :9

Sequence 1:	NP_651660.1	Gene:	CG11837 / 43429	FlyBaseID:	FBgn0039627	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_079723.1	Gene:	Dimt1 / 66254	MGIID:	1913504	Length:	313	Species:	Mus musculus

Alignment Length:	314	Identity:	214/314 - (68%)
Similarity:	256/314 - (81%)	Gaps:	9/314 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPKVTKEKKSRIHNDVQKQ--------GIVFNKDFGQHILKNPLVITTMLEKAALRATDVVLEIG 57
            |||......|| ..|.|:|        |::||...|||||||||::.::::|||||.||||||:|
Mouse     1 MPKAKSAASSR-RRDRQEQRRELKRAGGLMFNTGIGQHILKNPLIVNSIIDKAALRPTDVVLEVG 64

  Fly    58 PGTGNMTVRMLERAKKVIACEIDTRLAAELQKRVQATPLQPKLQVLIGDFLKAELPFFDLCIANV 122
            ||||||||::||:||||:|||:|.||.|||.||||.|||..|||||:||.||::|||||.|:||:
Mouse    65 PGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPLASKLQVLVGDVLKSDLPFFDACVANL 129

  Fly   123 PYQISSPLIFKLLLHRPLFRCAVLMFQREFAERLVAKPGDKLYCRLSINTQLLARVDMLMKVGKN 187
            |||||||.:||||||||.||||:||||||||.|||||||||||||||||||||||||.|||||||
Mouse   130 PYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKN 194

  Fly   188 NFRPPPKVESSVVRLEPKNPPPPVNFTEWDGLTRIAFLRKNKTLAATFKVTSVLEMLEKNYKLYR 252
            ||||||||||||||:||||||||:||.|||||.||.|:||||||:|.||.::|.::|||||:::.
Mouse   195 NFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHC 259

  Fly   253 SLRNEPIEDDFKMQDKVISILEEQDMAAKRARSMDIDDFMRLLLAFNSAGIHFN 306
            |::|..|.:||.:.||:..||.....:.|||||||||||:|||..||:.||||:
Mouse   260 SVQNTVIPEDFSIADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11837	NP_651660.1	PTZ00338	16..305	CDD:240367	206/296 (70%)
Dimt1	NP_079723.1	PTZ00338	27..312	CDD:240367	204/284 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848290
Domainoid	1	1.000	375	1.000	Domainoid score	I865
eggNOG	1	0.900	-	-		E1_COG0030
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7047
Inparanoid	1	1.050	437	1.000	Inparanoid score	I1671
Isobase	1	0.950	-	0	Normalized mean entropy	S279
OMA	1	1.010	-	-		QHG53890
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002924
OrthoInspector	1	1.000	-	-		oto94389
orthoMCL	1	0.900	-	-		OOG6_100569
Panther	1	1.100	-	-	LDO	PTHR11727
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R317
SonicParanoid	1	1.000	-	-		X3272
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.740