DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11837 and DIMT1

DIOPT Version :9

Sequence 1:	NP_651660.1	Gene:	CG11837 / 43429	FlyBaseID:	FBgn0039627	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_055288.1	Gene:	DIMT1 / 27292	HGNCID:	30217	Length:	313	Species:	Homo sapiens

Alignment Length:	313	Identity:	211/313 - (67%)
Similarity:	253/313 - (80%)	Gaps:	7/313 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPKVTKEKKSRIHNDVQKQ-------GIVFNKDFGQHILKNPLVITTMLEKAALRATDVVLEIGP 58
            ||||......|.....:::       |::||...|||||||||:|.::::|||||.||||||:||
Human     1 MPKVKSGAIGRRRGRQEQRRELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGP 65

  Fly    59 GTGNMTVRMLERAKKVIACEIDTRLAAELQKRVQATPLQPKLQVLIGDFLKAELPFFDLCIANVP 123
            |||||||::||:||||:|||:|.||.|||.||||.||:..|||||:||.||.:|||||.|:||:|
Human    66 GTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLP 130

  Fly   124 YQISSPLIFKLLLHRPLFRCAVLMFQREFAERLVAKPGDKLYCRLSINTQLLARVDMLMKVGKNN 188
            ||||||.:||||||||.||||:||||||||.|||||||||||||||||||||||||.||||||||
Human   131 YQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNN 195

  Fly   189 FRPPPKVESSVVRLEPKNPPPPVNFTEWDGLTRIAFLRKNKTLAATFKVTSVLEMLEKNYKLYRS 253
            |||||||||||||:||||||||:||.|||||.||.|:||||||:|.||.::|.::|||||:::.|
Human   196 FRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCS 260

  Fly   254 LRNEPIEDDFKMQDKVISILEEQDMAAKRARSMDIDDFMRLLLAFNSAGIHFN 306
            :.|..|.:||.:.||:..||.....:.|||||||||||:|||..||:.||||:
Human   261 VHNIIIPEDFSIADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11837	NP_651660.1	PTZ00338	16..305	CDD:240367	204/295 (69%)
DIMT1	NP_055288.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21		5/19 (26%)
DIMT1	NP_055288.1	PTZ00338	24..312	CDD:240367	204/287 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157905
Domainoid	1	1.000	370	1.000	Domainoid score	I908
eggNOG	1	0.900	-	-		E1_COG0030
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7047
Inparanoid	1	1.050	432	1.000	Inparanoid score	I1717
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53890
OrthoDB	1	1.010	-	-		D240437at33208
OrthoFinder	1	1.000	-	-		FOG0002924
OrthoInspector	1	1.000	-	-		oto90806
orthoMCL	1	0.900	-	-		OOG6_100569
Panther	1	1.100	-	-	LDO	PTHR11727
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R317
SonicParanoid	1	1.000	-	-		X3272
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800