Protein Alignment Pkc98E and TPK2

DIOPT Version :10

• Sequence 1: NP_524545.2
• Gene: Pkc98E / 43428
• FlyBaseID: FBgn0003093
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: NP_015121.1
• Gene: TPK2 / 855898
• SGDID: S000006124
• Length: 380
• Species: Saccharomyces cerevisiae
• Alignment Length: 298
• Identity: 125/298 - (41%)
• Similarity: 183/298 - (61%)
• Gaps: 6/298 - (2%)

  Fly   401 GKCSLLDFNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTEKRILALAAN 465
            ||.:|.||..::.||.||||:|.|.........||||||||..:::...|:.|..|:|:|.| ..
Yeast    63 GKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKL-VE 126

  Fly   466 HPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQFLHTHGVIY 530
            ||||..:...||....:|.||:|:.||:|...::|::||....|.||||||.|||::||.|.:||
Yeast   127 HPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIY 191

  Fly   531 RDLKLDNILLDQEGHCKLADFGMCKEGIMNGMLTTTFCGTPDYIAPEILKEQEYGASVDWWALGV 595
            ||||.:|||||:.||.|:.|||..||   ...:|.|.||||||||||::..:.|..|||||:|||
Yeast   192 RDLKPENILLDRNGHIKITDFGFAKE---VQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGV 253

  Fly   596 LMYEMMAGQPPFEADNEDELFDSIMHDDVLYPVWLSREAVSILKGFLTKNPEQRLG-CTGDENEI 659
            |:|||:||..||......:.::.|:...|:||.:...:.|.:|...:|.:..:|:| ......:|
Yeast   254 LIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDI 318

  Fly   660 RKHPFFAKLDWKELEKRNIKPPFRPKMKNP-RDANNFD 696
            :.||:|:::.|:.|..::|:.|:.|.:.:. .|.:.||
Yeast   319 KAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFD 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc98E	NP_524545.2	C2_PKC_epsilon	1..134	CDD:175981
		C1_nPKC_epsilon-like_rpt1	171..230	CDD:410385
		C1_nPKC_epsilon-like_rpt2	250..304	CDD:410388
		STKc_nPKC_epsilon	412..729	CDD:270743	120/287 (42%)
TPK2	NP_015121.1	STKc_PKA_like	69..358	CDD:270732	122/292 (42%)