Protein Alignment Pkc98E and Prkcq

DIOPT Version :10

• Sequence 1: NP_524545.2
• Gene: Pkc98E / 43428
• FlyBaseID: FBgn0003093
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: NP_001263650.1
• Gene: Prkcq / 85420
• RGDID: 620968
• Length: 707
• Species: Rattus norvegicus
• Alignment Length: 729
• Identity: 307/729 - (42%)
• Similarity: 428/729 - (58%)
• Gaps: 86/729 - (11%)

  Fly    36 QLIDPYVSIDVDE----SHFDRATTRPKTFDPVWNEQFVHDVTN-------VSNINLTVFHDAAL 89
            :.::||.::.|.|    .:......:..|..|.|:..|...:..       |...|:.:..:..:
  Rat    23 EAVNPYCAVLVKEYVESENGQMYIQKKPTMYPPWDSTFDAHINKGRVMQIIVKGKNVDLISETTV 87

  Fly    90 PPDDFVANCIISFEDLMQSETAVQDLWVNLEPQGKI----HVIIELKNRTDKAKAEAVVEHTVAV 150
            .        :.|..:..:......::|:.|:|||::    ...:|:.:..|.:
  Rat    88 E--------LYSLAERCRKNNGRTEIWLELKPQGRMLMNARYFLEMSDTKDMS------------ 132

  Fly   151 NKEFKERAGF---NRRRGAMRR-RVHQVNGHKFMATFLRQPTFCSHCREFIWGIGKQGYQCQVCT 211
              || |..||   :.||||::: :||.|..|:|.|||..||||||.|.||:||:.||||||:.|.
  Rat   133 --EF-ENEGFFALHHRRGAIKQAKVHHVKCHEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCN 194

  Fly   212 LVVHKKCHLSVVSKCPG----MRDEQPAKVEMVPAGQRFNVNLPHRFVVHSYKRFTFCDHCGSLL 272
            ..:||||...|::||.|    .|:....|       :||.:::||||.|::||..|||:|||:||
  Rat   195 AAIHKKCIDKVIAKCTGSAINSRETMFHK-------ERFKIDMPHRFKVYNYKSPTFCEHCGTLL 252

  Fly   273 YGLIKQGLQCETCGMNVHKRCQKNVANTCGINTKQMAEILSSLGISPDKQQPRRSKYLNQQGG-E 336
            :||.:|||:|:.||||||.|||..|||.||||.|.|||.|:.:..:...:..|.|:::.::|. |
  Rat   253 WGLARQGLKCDACGMNVHHRCQTKVANLCGINQKLMAEALAMIESTQQARTLRDSEHIFREGPIE 317

  Fly   337 DNYGASLGAD---------GDGAP-GQSFRSCALSVDSLATSTTTMTSGYNSSSCMSLAVTGSGG 391
            .::..|:.::         |...| |..:.|.....|..|.......:...:|..:.|.:.
  Rat   318 ISFPRSIKSETRPPCVPTPGKKEPQGICWESPLDGADKTAQPPEPEVNLQRASLQLKLKID---- 378

  Fly   392 VGATGETRPGKCSLLDFNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTE 456
                           ||...|:|||||||||.|||.|.|.:.:|||.||||.::.||||:|||.|
  Rat   379 ---------------DFILHKMLGKGSFGKVFLAEFKRTKQFFAIKALKKDVVLMDDDVECTMVE 428

  Fly   457 KRILALAANHPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQ 521
            ||:|:||..|||||.:...|||.:.|||||||:||||||:.||...:|:.|||.|||||:.|.||
  Rat   429 KRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQ 493

  Fly   522 FLHTHGVIYRDLKLDNILLDQEGHCKLADFGMCKEGIMNGMLTTTFCGTPDYIAPEILKEQEYGA 586
            |||:.|::||||||||||||::||.|:||||||||.::....|.||||||||||||||..|:|..
  Rat   494 FLHSKGIVYRDLKLDNILLDRDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNH 558

  Fly   587 SVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLYPVWLSREAVSILKGFLTKNPEQRLG 651
            |||||:.|||:|||:.||.||...:|:|||.||..|:..||.||.|||..:|.....:.||:|||
  Rat   559 SVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEREAKDLLVKLFVREPEKRLG 623

  Fly   652 CTGDENEIRKHPFFAKLDWKELEKRNIKPPFRPKMKNPRDANNFDAEFTKEDPVLTPIGNEVVRC 716
            ..||   ||:||.|.:::|:|||::.|.||||||:|:|.|.:|||.||..|.|.|:.....::..
  Rat   624 VRGD---IRQHPLFREINWEELERKEIDPPFRPKVKSPYDCSNFDKEFLSEKPRLSFADRALINS 685

  Fly   717 INQDEFAGFSFVNP 730
            ::|:.|:.|||:||
  Rat   686 MDQNMFSNFSFINP 699

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc98E	NP_524545.2	C2_PKC_epsilon	1..134	CDD:175981	17/112 (15%)
		C1_nPKC_epsilon-like_rpt1	171..230	CDD:410385	34/62 (55%)
		C1_nPKC_epsilon-like_rpt2	250..304	CDD:410388	35/53 (66%)
		STKc_nPKC_epsilon	412..729	CDD:270743	183/316 (58%)
Prkcq	NP_001263650.1	C1_nPKC_theta-like_rpt1	153..213	CDD:410384	34/59 (58%)
		C1_nPKC_theta-like_rpt2	232..281	CDD:410387	32/48 (67%)
		STKc_nPKC_theta	374..704	CDD:270770	188/348 (54%)