DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pkc98E and RSH3

DIOPT Version :9

Sequence 1:	NP_001287577.1	Gene:	Pkc98E / 43428	FlyBaseID:	FBgn0003093	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	NP_173094.4	Gene:	RSH3 / 838214	AraportID:	AT1G16440	Length:	499	Species:	Arabidopsis thaliana

Alignment Length:	522	Identity:	136/522 - (26%)
Similarity:	221/522 - (42%)	Gaps:	132/522 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   275 LIKQGLQCETCGMNVHKRCQKNVAN-TCGINTKQMAEILSSLGISPDKQQPRRSKYLNQQGGEDN 338
            |:|.|.:..:...:.|:....|.:| .|                  .:|:||:.|   |:..|.|
plant     2 LLKPGNKLVSPETSHHRDSASNSSNHKC------------------QQQKPRKDK---QKQVEQN 45

  Fly   339 YGASLGADGDGAPGQSFRSCALSVDSLATSTTTMTSGYN------SSSCMSLAVTGSGGVGATGE 397
                              :..:....:.:.:|.:.|.:|      |::..|.:...|......|:
plant    46 ------------------TKKIEEHQIKSESTLLISNHNVNMSSQSNNSESTSTNNSSKPHTGGD 92

  Fly   398 ----------TRPGKCSLLDFNFIKVLGKGSFGKVMLAEKKGTD--EIYAIKVLKKDAIIQDDDV 450
                      :|..|..:.||..:|.||.|..|.|.|.|.||.:  ..:|:||:.|.:::..:.:
plant    93 IRWDAVNSLKSRGIKLGISDFRVLKRLGYGDIGSVYLVELKGANPTTYFAMKVMDKASLVSRNKL 157

  Fly   451 DCTMTEKRILALAANHPFLTALHSCFQTPDRLFFVMEYVNGGDL--MFQIQKARRFEASRAAFYA 513
            ....||:.||: ..:||||..|:|.|:|......|||:.:||:|  :.|.|..:.|....|.|:|
plant   158 LRAQTEREILS-QLDHPFLPTLYSHFETDKFYCLVMEFCSGGNLYSLRQKQPNKCFTEDAARFFA 221

  Fly   514 AEVTLALQFLHTHGVIYRDLKLDNILLDQEGHCKLADFGM---CKEG-----IMNGMLTT----- 565
            :||.|||::||..|::|||||.:|:|:..:||..|:||.:   |...     ..||..||
plant   222 SEVLLALEYLHMLGIVYRDLKPENVLVRDDGHIMLSDFDLSLRCSVNPTLVKSFNGGGTTGIIDD 286

  Fly   566 ------------------------------------------------TFCGTPDYIAPEILKEQ 582
                                                            :|.||.:|:||||:|.:
plant   287 NAAVQGCYQPSAFFPRMLQSSKKNRKSKSDFDGSLPELMAEPTNVKSMSFVGTHEYLAPEIIKNE 351

  Fly   583 EYGASVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLYPVW--LSREAVSILKGFLTKN 645
            .:|::||||..|:.:||::.|..||:.........:::...:.:|.:  :|..|..::||.|.|.
plant   352 GHGSAVDWWTFGIFIYELLHGATPFKGQGNKATLYNVIGQPLRFPEYSQVSSTAKDLIKGLLVKE 416

  Fly   646 PEQRLGCTGDENEIRKHPFFAKLDWKELEKRNIKPPFRPKMKNPRDANNFDAEFTKEDPVLTPIG 710
            |:.|:.......||::||||..::|..:  |...||..|:   |.|   |.....||...|.|..
plant   417 PQNRIAYKRGATEIKQHPFFEGVNWALI--RGETPPHLPE---PVD---FSCYVKKEKESLPPAA 473

  Fly   711 NE 712
            .|
plant   474 TE 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pkc98E	NP_001287577.1	C2_PKC_epsilon	1..134	CDD:175981
		C1_1	177..228	CDD:278556
		C1_1	252..304	CDD:278556	7/29 (24%)
		STKc_nPKC_epsilon	412..729	CDD:270743	111/368 (30%)
RSH3	NP_173094.4	STKc_phototropin_like	111..457	CDD:270726	106/351 (30%)
RSH3	NP_173094.4	S_TKc	113..436	CDD:214567	97/323 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	206	1.000	Inparanoid score	I1276
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960