| Sequence 1: | NP_001287577.1 | Gene: | Pkc98E / 43428 | FlyBaseID: | FBgn0003093 | Length: | 739 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_005391.1 | Gene: | PRKCE / 5581 | HGNCID: | 9401 | Length: | 737 | Species: | Homo sapiens |
| Alignment Length: | 758 | Identity: | 437/758 - (57%) |
|---|---|---|---|
| Similarity: | 551/758 - (72%) | Gaps: | 49/758 - (6%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1 MFTGKLQIKVCEASGLRPTDFQKRHNLTFGKLADEQLIDPYVSIDVDESHFDRATTRPKTFDPVW 65
Fly 66 NEQFVHDVTNVSNINLTVFHDAALPPDDFVANCIISFEDLMQSETAVQDLWVNLEPQGKIHVIIE 130
Fly 131 LKNRTDKAKAEAVVEHTVAVNKE--FKERAGFNRRRGAMRRRVHQVNGHKFMATFLRQPTFCSHC 193
Fly 194 REFIWG-IGKQGYQCQVCTLVVHKKCHLSVVSKCPGM-RDEQPAKVEMVPAGQRFNVNLPHRFVV 256
Fly 257 HSYKRFTFCDHCGSLLYGLIKQGLQCETCGMNVHKRCQKNVANTCGINTKQMAEILSSLGISPDK 321
Fly 322 ---QQPRRSKYLNQQGGEDNYGASLGADGDGAPGQSFRS-------CALSVDSLATSTTTMTSGY 376
Fly 377 NSSSCMSLAVTGSGGV---GATGETRPGKCSLL---DFNFIKVLGKGSFGKVMLAEKKGTDEIYA 435
Fly 436 IKVLKKDAIIQDDDVDCTMTEKRILALAANHPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQK 500
Fly 501 ARRFEASRAAFYAAEVTLALQFLHTHGVIYRDLKLDNILLDQEGHCKLADFGMCKEGIMNGMLTT 565
Fly 566 TFCGTPDYIAPEILKEQEYGASVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLYPVWL 630
Fly 631 SREAVSILKGFLTKNPEQRLGCTGDEN---EIRKHPFFAKLDWKELEKRNIKPPFRPKMKNPRDA 692
Fly 693 NNFDAEFTKEDPVLTPIGNEVVRCINQDEFAGFSFVNPKFGPE 735 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Pkc98E | NP_001287577.1 | C2_PKC_epsilon | 1..134 | CDD:175981 | 59/132 (45%) |
| C1_1 | 177..228 | CDD:278556 | 40/51 (78%) | ||
| C1_1 | 252..304 | CDD:278556 | 34/51 (67%) | ||
| STKc_nPKC_epsilon | 412..729 | CDD:270743 | 241/319 (76%) | ||
| PRKCE | NP_005391.1 | C2_PKC_epsilon | 3..135 | CDD:175981 | 59/133 (44%) |
| C1_nPKC_epsilon-like_rpt1 | 161..224 | CDD:410385 | 50/62 (81%) | ||
| Interaction with actin. /evidence=ECO:0000250 | 223..228 | 0/4 (0%) | |||
| C1_nPKC_epsilon-like_rpt2 | 241..295 | CDD:410388 | 35/53 (66%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 325..356 | 8/35 (23%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 370..398 | 7/27 (26%) | |||
| STKc_nPKC_epsilon | 412..732 | CDD:270743 | 241/323 (75%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 446 | 1.000 | Domainoid score | I527 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG0694 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H48343 | |
| Inparanoid | 1 | 1.050 | 874 | 1.000 | Inparanoid score | I414 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S892 |
| OMA | 1 | 1.010 | - | - | QHG51944 | |
| OrthoDB | 1 | 1.010 | - | - | D222529at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000117 | |
| OrthoInspector | 1 | 1.000 | - | - | otm40481 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_102972 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR24356 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R891 |
| SonicParanoid | 1 | 1.000 | - | - | X125 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 16 | 15.820 | |||||