Protein Alignment Pkc98E and prkcq

DIOPT Version :10

• Sequence 1: NP_524545.2
• Gene: Pkc98E / 43428
• FlyBaseID: FBgn0003093
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: XP_009298659.1
• Gene: prkcq / 555521
• ZFINID: ZDB-GENE-041210-195
• Length: 719
• Species: Danio rerio
• Alignment Length: 720
• Identity: 314/720 - (43%)
• Similarity: 433/720 - (60%)
• Gaps: 54/720 - (7%)

  Fly    35 EQLIDPYVSIDVDES-HFDRATT----RPKTFDPVWNEQF---------VHDVTNVSNINLTVFH 85
            |::::||.::.:.|: ..::...    || |..|.|:..|         :|.|.......|..
Zfish    22 EEVLNPYCAVYMKEAVETEKGQVYKQKRP-TMYPPWSSTFDAHVHKGRVMHVVVKDKTAELKT-- 83

  Fly    86 DAALPPDDFVANCIISFEDLMQSETAVQDLWVNLEPQGKIHVIIELKNRTDKAKAEAVVEHTVAV 150
            :|.:..|...:.|        :.|....::||.|:|||::  ::|.:...:::.|....|.....
Zfish    84 EATVQLDTLASRC--------KKENGKLEIWVELKPQGRL--LMEARYFLERSDAAGHGEGDGET 138

  Fly   151 NKEFKERAGFNRRRGAMRR-RVHQVNGHKFMATFLRQPTFCSHCREFIWGIGKQGYQCQVCTLVV 214
            .:|.:.....:.||||::: :||.|..|:|.|||..||||||.|:||:||:.||||||:.|...:
Zfish   139 EREKEGVFALHHRRGAIKQAKVHVVKCHEFTATFFPQPTFCSVCKEFVWGLNKQGYQCRQCNAAI 203

  Fly   215 HKKCHLSVVSKCPGMRDEQPAKVEMVPAGQRFNVNLPHRFVVHSYKRFTFCDHCGSLLYGLIKQG 279
            ||||...|::||.|  ....:|..|:.. :||.:::||||.|::|...|||:|||:||:||.:||
Zfish   204 HKKCIDKVIAKCTG--SAVNSKETMIHK-ERFKIDMPHRFKVYNYMSPTFCEHCGTLLWGLARQG 265

  Fly   280 LQCETCGMNVHKRCQKNVANTCGINTKQMAEILSSLGISPDKQQPRRSKYLNQQGGEDNYGASLG 344
            |:||.||||||.:|||.|||.||:|.|.|||.|:.  |...:||.|.|:.....|.|    ..:.
Zfish   266 LKCEECGMNVHHKCQKKVANLCGVNQKLMAEALAM--IESTQQQARSSRDTETVGRE----GPVS 324

  Fly   345 ADGDGAPGQSFRSCALSVDSLATSTTTMTSGYNSSSCMSLAVTGSGGVGATGETRP--------- 400
            ||..|...:.  |..|::..|..:.......:...|..|.|   .|...:..|..|
Zfish   325 ADQPGVIREP--SGRLAISPLTPAPPLPRKEHQGISWDSPA---DGRRPSLEEPEPLYATPRKEH 384

  Fly   401 GKCSLLDFNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTEKRILALAAN 465
            .|.::..|...|:|||||||||.|||.||:.:.:|:|.||||.::.||||:|||.|:|:|:||.:
Zfish   385 HKFTIDSFILHKMLGKGSFGKVFLAELKGSGQFFAVKALKKDVVLMDDDVECTMVERRVLSLAWD 449

  Fly   466 HPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQFLHTHGVIY 530
            |||||.|:..|||.:.|||||||:|||||||.||...||:..|:.|||||:...|||||:.|::|
Zfish   450 HPFLTHLYCTFQTKENLFFVMEYLNGGDLMFHIQTCHRFDLPRSTFYAAEIICGLQFLHSKGIVY 514

  Fly   531 RDLKLDNILLDQEGHCKLADFGMCKEGIMNGMLTTTFCGTPDYIAPEILKEQEYGASVDWWALGV 595
            |||||||||||.:||.|:||||||||.|:....|.||||||||||||||..|:||.|||||:.||
Zfish   515 RDLKLDNILLDTDGHIKIADFGMCKENIIGEARTCTFCGTPDYIAPEILLGQKYGTSVDWWSFGV 579

  Fly   596 LMYEMMAGQPPFEADNEDELFDSIMHDDVLYPVWLSREAVSILKGFLTKNPEQRLGCTGDENEIR 660
            |:|||:.||.||...:|:|||.||..||..||.||:|:|..||.....:.||:|||..|:   ||
Zfish   580 LLYEMLIGQSPFHGHDEEELFQSIRTDDPCYPRWLTRDARDILVKLFVREPERRLGVKGN---IR 641

  Fly   661 KHPFFAKLDWKELEKRNIKPPFRPKMKNPRDANNFDAEFTKEDPVLTPIGNEVVRCINQDEFAGF 725
            :||||.:.||..||:|.::|||:|.:|:..|.:|||.||..|.|.|:.....::..::|..|..|
Zfish   642 QHPFFRETDWSALEERQVEPPFKPTVKSANDCSNFDKEFINEKPRLSVTDRMMINSMDQSMFENF 706

  Fly   726 SFVNP 730
            ||:||
Zfish   707 SFINP 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc98E	NP_524545.2	C2_PKC_epsilon	1..134	CDD:175981	24/112 (21%)
		C1_nPKC_epsilon-like_rpt1	171..230	CDD:410385	34/58 (59%)
		C1_nPKC_epsilon-like_rpt2	250..304	CDD:410388	35/53 (66%)
		STKc_nPKC_epsilon	412..729	CDD:270743	181/316 (57%)
prkcq	XP_009298659.1	C1_nPKC_theta-like_rpt1	159..219	CDD:410384	34/61 (56%)
		C1_nPKC_theta-like_rpt2	238..287	CDD:410387	32/48 (67%)
		STKc_nPKC_theta	386..716	CDD:270770	185/329 (56%)