Protein Alignment Pkc98E and Pkc53E

DIOPT Version :10

• Sequence 1: NP_524545.2
• Gene: Pkc98E / 43428
• FlyBaseID: FBgn0003093
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: NP_725626.1
• Gene: Pkc53E / 48311
• FlyBaseID: FBgn0003091
• Length: 679
• Species: Drosophila melanogaster
• Alignment Length: 717
• Identity: 308/717 - (42%)
• Similarity: 389/717 - (54%)
• Gaps: 179/717 - (24%)

  Fly   138 AKAEAVVEHTVAVNKEFKERAGFNRRRGAMRRR-VHQVNGHKFMATFLRQPTFCSHCREFI---- 197
            |:.|||.|:      :.|.|.    |:||:::: |..|..|.|:|.|.:||||||||::||
  Fly    16 AEGEAVGEN------KMKSRL----RKGALKKKNVFNVKDHCFIARFFKQPTFCSHCKDFICGYQ 70

  Fly   198 ----W-GIGKQGYQCQVCTLVVHKKCHLSVVSKCPGMR---DEQPAKVEMVPAGQRFNVNLPHRF 254
                | |.||||:|||||:.||||:||..|...|||..   |....|.:             |.|
  Fly    71 SGYAWMGFGKQGFQCQVCSYVVHKRCHEYVTFICPGKDKGIDSDSPKTQ-------------HNF 122

  Fly   255 VVHSYKRFTFCDHCGSLLYGLIKQGLQCETCGMNVHKRCQKNVANTCG-------------INTK 306
            ...:|...||||||||||||:..|||:|..|.||||.||::||.:.||             ||.|
  Fly   123 EPFTYAGPTFCDHCGSLLYGIYHQGLKCSACDMNVHARCKENVPSLCGCDHTERRGRIYLEINVK 187

  Fly   307 ------QMAEILSSLGISP---------------DKQQPRRS----------------------- 327
                  |:.|..:.:.:.|               ||.|.::.
  Fly   188 ENLLTVQIKEGRNLIPMDPNGLSDPYVKVKLIPDDKDQSKKKTRTIKACLNPVWNETLTYDLKPE 252

  Fly   328 -----------------------------------------KYLNQQGGEDNYGASLGADGDG-- 349
                                                     |.|.|..|| .|......|...
  Fly   253 DKDRRILIEVWDWDRTSRNDFMGALSFGISEIIKNPTNGWFKLLTQDEGE-YYNVPCADDEQDLL 316

  Fly   350 ----APGQS----FRSCALSVDSLATSTTTMTSGYNSSSCMSLAVTGSGGVGATGETRPGKCSLL 406
                .|.|.    .||          .|.|.||.....            :.||
  Fly   317 KLKQKPSQKKPMVMRS----------DTNTHTSSKKDM------------IRAT----------- 348

  Fly   407 DFNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTEKRILALAANHPFLTA 471
            ||||||||||||||||:|||:||::|:||||:||||.|||||||:|||.|||:|||....|||..
  Fly   349 DFNFIKVLGKGSFGKVLLAERKGSEELYAIKILKKDVIIQDDDVECTMIEKRVLALGEKPPFLVQ 413

  Fly   472 LHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQFLHTHGVIYRDLKLD 536
            |||||||.||||||||||||||||||||:..:|:...|.|||||:...|.||||.|::|||||||
  Fly   414 LHSCFQTMDRLFFVMEYVNGGDLMFQIQQFGKFKEPVAVFYAAEIAAGLFFLHTKGILYRDLKLD 478

  Fly   537 NILLDQEGHCKLADFGMCKEGIMNGMLTTTFCGTPDYIAPEILKEQEYGASVDWWALGVLMYEMM 601
            |:|||.:||.|:||||||||.|:....|.|||||||||||||:..|.||.||||||.|||:|||:
  Fly   479 NVLLDADGHVKIADFGMCKENIVGDKTTKTFCGTPDYIAPEIILYQPYGKSVDWWAYGVLLYEML 543

  Fly   602 AGQPPFEADNEDELFDSIMHDDVLYPVWLSREAVSILKGFLTKNPEQRLGC-TGDENEIRKHPFF 665
            .|||||:.::|:|||.:|...:|.||..||:||....||||||.|.:|||| :..|.::|.||||
  Fly   544 VGQPPFDGEDEEELFAAITDHNVSYPKSLSKEAKEACKGFLTKQPNKRLGCGSSGEEDVRLHPFF 608

  Fly   666 AKLDWKELEKRNIKPPFRPKMKNPRDANNFDAEFTKEDPVLTPIGNEVVRCINQDEFAGFSFVNP 730
            .::||:::|.|.::|||:||:|:.:|.:|||.:||.|...|||.....:..::|.||.|||::||
  Fly   609 RRIDWEKIENREVQPPFKPKIKHRKDVSNFDKQFTSEKTDLTPTDKVFMMNLDQSEFVGFSYMNP 673

  Fly   731 KF 732
            ::
  Fly   674 EY 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc98E	NP_524545.2	C2_PKC_epsilon	1..134	CDD:175981
		C1_nPKC_epsilon-like_rpt1	171..230	CDD:410385	37/67 (55%)
		C1_nPKC_epsilon-like_rpt2	250..304	CDD:410388	30/66 (45%)
		STKc_nPKC_epsilon	412..729	CDD:270743	196/317 (62%)
Pkc53E	NP_725626.1	C1_cPKC_rpt1	44..110	CDD:410383	35/65 (54%)
		C1_cPKC_rpt2	120..173	CDD:410386	30/52 (58%)
		C2_PKC_alpha_gamma	177..307	CDD:175992	15/130 (12%)
		STKc_cPKC	353..672	CDD:270739	197/318 (62%)