Protein Alignment Pkc98E and for

DIOPT Version :10

• Sequence 1: NP_524545.2
• Gene: Pkc98E / 43428
• FlyBaseID: FBgn0003093
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: NP_477487.1
• Gene: for / 44817
• FlyBaseID: FBgn0000721
• Length: 1088
• Species: Drosophila melanogaster
• Alignment Length: 468
• Identity: 134/468 - (28%)
• Similarity: 219/468 - (46%)
• Gaps: 69/468 - (14%)

  Fly   289 VHKRCQKNVANTCG-INTKQMAEILSSLGISPDKQQP--------------RRSKYLNQQGG--- 335
            :.::|.:.:....| |...:.::.|.|:.|..|..:.              :|..|:.:||.
  Fly   609 IERQCFQTIMMRTGLIRQAEYSDFLKSVPIFKDLAEDTLIKISDVLEETHYQRGDYIVRQGARGD 673

  Fly   336 --------------------EDNYGASLGADGDGAPGQSFRSCALSVDSLATSTTTMTSGYNSSS 380
                                |:.:...||      .|..|...||..|.|.|:.....|. :..|
  Fly   674 TFFIISKGKVRVTIKQQDTQEEKFIRMLG------KGDFFGEKALQGDDLRTANIICESA-DGVS 731

  Fly   381 CMSL-------AVTGSGGV-------GATGETRPGK----CSLLDFNFIKVLGKGSFGKVMLAEK 427
            |:.:       .::....:       ||....:..:    .:|.|...|..||.|.||:|.|.:.
  Fly   732 CLVIDRETFNQLISNLDEIKHRYDDEGAMERRKINEEFRDINLTDLRVIATLGVGGFGRVELVQT 796

  Fly   428 KG-TDEIYAIKVLKKDAIIQDDDVDCTMTEKRILALAANHPFLTALHSCFQTPDRLFFVMEYVNG 491
            .| :...:|:|.:||..|::.......|:||.|:. .||..|:..|...|:....|:.:||...|
  Fly   797 NGDSSRSFALKQMKKSQIVETRQQQHIMSEKEIMG-EANCQFIVKLFKTFKDKKYLYMLMESCLG 860

  Fly   492 GDLMFQIQKARRFEASRAAFYAAEVTLALQFLHTHGVIYRDLKLDNILLDQEGHCKLADFGMCKE 556
            |:|...::....|:.|...||.|.|..|..:||:..:||||||.:|:||::.|:.||.|||..|:
  Fly   861 GELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIYRDLKPENLLLNERGYVKLVDFGFAKK 925

  Fly   557 GIMNGMLTTTFCGTPDYIAPEILKEQEYGASVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMH 621
             :..|..|.||||||:|:|||::..:.:..|.|:|:|||||:|::.|.|||...:....::.|:.
  Fly   926 -LQTGRKTWTFCGTPEYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFTGSDPMRTYNIILK 989

  Fly   622 --DDVLYPVWLSREAVSILKGFLTKNPEQRLGC-TGDENEIRKHPFFAKLDWKELEKRNIKPPFR 683
              |.:.:|..::|.|.:::|.....||.:|||. .|..:||:||.:|....|..|:...::||.:
  Fly   990 GIDAIEFPRNITRNASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYWWGLQNCTLEPPIK 1054

  Fly   684 PKMKNPRDANNFD 696
            |.:|:..|..|||
  Fly  1055 PAVKSVVDTTNFD 1067

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc98E	NP_524545.2	C2_PKC_epsilon	1..134	CDD:175981
		C1_nPKC_epsilon-like_rpt1	171..230	CDD:410385
		C1_nPKC_epsilon-like_rpt2	250..304	CDD:410388	2/15 (13%)
		STKc_nPKC_epsilon	412..729	CDD:270743	105/289 (36%)
for	NP_477487.1	DD_cGKI-alpha	385..432	CDD:213374
		CAP_ED	520..629	CDD:237999	3/19 (16%)
		CAP_ED	638..754	CDD:237999	19/122 (16%)
		STKc_cGK	783..1043	CDD:270724	96/261 (37%)