DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pkc98E and JIL-1

DIOPT Version :10

Sequence 1:NP_524545.2 Gene:Pkc98E / 43428 FlyBaseID:FBgn0003093 Length:739 Species:Drosophila melanogaster
Sequence 2:NP_648432.1 Gene:JIL-1 / 39241 FlyBaseID:FBgn0020412 Length:1207 Species:Drosophila melanogaster


Alignment Length:470 Identity:155/470 - (32%)
Similarity:242/470 - (51%) Gaps:56/470 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly   305 TKQMAEILS-SLGISPDKQQPRRSKYLNQQGGE--------DNYGASLG---ADGDGAPGQSFRS 357
            |..:|:|:. |...|.|.:.|.| :|.:|...|        |...:||.   ::...|...:..:
  Fly   137 TTNVADIVCISDAESEDGRDPER-EYYDQDMEEDEPNGIEIDESSSSLSKAKSNNAAAAAAAAAA 200

  Fly   358 CALSVDSLATSTTTMTSGYNSSSCMSLAVTGSG---GVGATGETR-------PGKCSLLDFNFIK 412
            .|.:..|.|:|:||.:....:|:...|.:....   .:.|..:.:       ....||.||..|:
  Fly   201 AAAAAASKASSSTTPSYAMPTSNSTPLDLDNEAHQRDLEAVTDLKYYVKLYSDEAVSLNDFKIIR 265

  Fly   413 VLGKGSFGKVMLAEK---KGTDEIYAIKVLKKDAIIQD-DDVDCTMTEKRILALAANHPFLTALH 473
            |||.|::|:|.|..|   ....::||:|||.|..::|. ...:.|.||:.:|.....:|||.:||
  Fly   266 VLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVVLEAIQRNPFLVSLH 330

  Fly   474 SCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQFLHTHGVIYRDLKLDNI 538
            ..||:..:|:.|:::.|||:|...:..:..||.||...|.|||.|||:.||..|:||||:||:||
  Fly   331 YAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLALEQLHQLGIIYRDIKLENI 395

  Fly   539 LLDQEGHCKLADFGMCKEGIMNGMLTT-------TFCGTPDYIAPEILKEQEYG--ASVDWWALG 594
            |||.|||..|:|||:.|      :||.       :||||.:|:||||::....|  ::||||::|
  Fly   396 LLDGEGHIVLSDFGLSK------ILTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAVDWWSVG 454

  Fly   595 VLMYEMMAGQPPFEADN----EDELFDSIMHDDVLYPVWLSREAVSILKGFLTKNPEQRLGCT-G 654
            ||.:|::.|..||...:    :.|:...|..:..:.|...|..|...:...|.|||::|||.. .
  Fly   455 VLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSANARDFVLKMLEKNPKRRLGGNHR 519

  Fly   655 DENEIRKHPFFAKLDWKELEKRNIKPPFRPKMKNPRDANNFDAEFT---KEDPVLTPIGNEVVRC 716
            |.:||::||||..::|:||..:..|.|::|.:....|..||..|||   .|||......:.:   
  Fly   520 DASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDVQNFSNEFTDQVPEDPECDAPPSRI--- 581

  Fly   717 INQDEFAGFSFVNPK 731
               ..|.|:::|.|:
  Fly   582 ---RLFRGYTYVAPE 593

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pkc98ENP_524545.2 C2_PKC_epsilon 1..134 CDD:175981
C1_nPKC_epsilon-like_rpt1 171..230 CDD:410385
C1_nPKC_epsilon-like_rpt2 250..304 CDD:410388
STKc_nPKC_epsilon 412..729 CDD:270743 124/337 (37%)
JIL-1NP_648432.1 STKc_MSK_N 266..533 CDD:270735 107/272 (39%)
S_TK_X 532..591 CDD:214529 17/64 (27%)
S_TKc 632..886 CDD:214567
Blue background indicates that the domain is not in the aligned region.

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