Protein Alignment Pkc98E and Prkaca

DIOPT Version :10

• Sequence 1: NP_524545.2
• Gene: Pkc98E / 43428
• FlyBaseID: FBgn0003093
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: NP_001094392.1
• Gene: Prkaca / 25636
• RGDID: 3389
• Length: 351
• Species: Rattus norvegicus
• Alignment Length: 309
• Identity: 127/309 - (41%)
• Similarity: 190/309 - (61%)
• Gaps: 7/309 - (2%)

  Fly   397 ETRPGKCSLLD-FNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTEKRIL 460
            ||.....:.|| |:.||.||.||||:|||.:.|.:...||:|:|.|..:::...::.|:.|||||
  Rat    32 ETPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRIL 96

  Fly   461 ALAANHPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQFLHT 525
            . |.|.|||..|...|:....|:.|||||.||::...:::..||....|.||||::.|..::||:
  Rat    97 Q-AVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160

  Fly   526 HGVIYRDLKLDNILLDQEGHCKLADFGMCKEGIMNGMLTTTFCGTPDYIAPEILKEQEYGASVDW 590
            ..:||||||.:|:|:||:|:.::.|||..|.  :.|. |.|.||||:|:||||:..:.|..:|||
  Rat   161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR--VKGR-TWTLCGTPEYLAPEIILSKGYNKAVDW 222

  Fly   591 WALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLYPVWLSREAVSILKGFLTKNPEQRLG-CTG 654
            ||||||:|||.||.|||.||...::::.|:...|.:|...|.:...:|:..|..:..:|.| ...
  Rat   223 WALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKN 287

  Fly   655 DENEIRKHPFFAKLDWKELEKRNIKPPFRPKMKNPRDANNFDAEFTKED 703
            ..|:|:.|.:||..||..:.:|.::.||.||.|.|.|.:||| ::.:|:
  Rat   288 GVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD-DYEEEE 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc98E	NP_524545.2	C2_PKC_epsilon	1..134	CDD:175981
		C1_nPKC_epsilon-like_rpt1	171..230	CDD:410385
		C1_nPKC_epsilon-like_rpt2	250..304	CDD:410388
		STKc_nPKC_epsilon	412..729	CDD:270743	121/293 (41%)
Prkaca	NP_001094392.1	STKc_PKA	42..331	CDD:271111	123/293 (42%)