DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pkc98E and F47F2.1

DIOPT Version :10

Sequence 1:NP_524545.2 Gene:Pkc98E / 43428 FlyBaseID:FBgn0003093 Length:739 Species:Drosophila melanogaster
Sequence 2:NP_508671.2 Gene:F47F2.1 / 180673 WormBaseID:WBGene00018569 Length:398 Species:Caenorhabditis elegans


Alignment Length:390 Identity:132/390 - (33%)
Similarity:201/390 - (51%) Gaps:40/390 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   355 FRSCALSVDSLATSTTTMTSGYNSSSC---MSLAVT--------GSGGVGATGETRPGKC----- 403
            ||.|.. ...|.:|:|:........||   .|.:.|        |:..|....|....|.     
 Worm    18 FRICRF-FRRLMSSSTSSVESVEDESCSNECSASFTFDTNNNSRGNNQVNELAEETHMKLSITPT 81

  Fly   404 ----SLLDFNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTEKRILALAA 464
                ||.....|..:|||:||:|.||..|.|...||:|||....::..........|||:| |..
 Worm    82 RESFSLSQLERIITIGKGTFGRVELARDKITGAHYALKVLNIRRVVDMRQTQHVHNEKRVL-LQL 145

  Fly   465 NHPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQFLHTHGVI 529
            .|||:..:::..:..:.|:.:||:|.||::...::.:|.|..|.|.|||:|:..||:::|:.|::
 Worm   146 KHPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMARFYASEIVCALEYIHSLGIV 210

  Fly   530 YRDLKLDNILLDQEGHCKLADFGMCKEGIMNGML---TTTFCGTPDYIAPEILKEQEYGASVDWW 591
            |||||.:|::|.:|||.|:||||..||      |   |.|.||||||:|||.|....:...||||
 Worm   211 YRDLKPENLMLSKEGHIKMADFGFAKE------LRDRTYTICGTPDYLAPESLARTGHNKGVDWW 269

  Fly   592 ALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLYPVWLSREAVSILKGFLTKNPEQRLGC-TGD 655
            |||:|:||||.|:|||......|::|:|:...:.:|...:..|..::|..|..:..||:|| ...
 Worm   270 ALGILIYEMMVGKPPFRGKTTSEIYDAIIEHKLKFPRSFNLAAKDLVKKLLEVDRTQRIGCMKNG 334

  Fly   656 ENEIRKHPFFAKLDWKELEKRNIKPPFRPKMKNPRDANNFDAEFTKEDPVLTPIGNEVVRCINQD 720
            ..:::.|.:|.|::|.:.....::||..|.:.:|.|..|||.  .:||....|:      |..:|
 Worm   335 TQDVKDHKWFEKVNWDDTLHLRVEPPIVPTLYHPGDTGNFDD--YEEDTTGGPL------CSQRD 391

  Fly   721  720
             Worm   392  391

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pkc98ENP_524545.2 C2_PKC_epsilon 1..134 CDD:175981
C1_nPKC_epsilon-like_rpt1 171..230 CDD:410385
C1_nPKC_epsilon-like_rpt2 250..304 CDD:410388
STKc_nPKC_epsilon 412..729 CDD:270743 115/313 (37%)
F47F2.1NP_508671.2 Protein Kinases, catalytic domain 88..379 CDD:473864 111/299 (37%)
Blue background indicates that the domain is not in the aligned region.

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