Protein Alignment Pkc98E and sax-1

DIOPT Version :10

• Sequence 1: NP_524545.2
• Gene: Pkc98E / 43428
• FlyBaseID: FBgn0003093
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: NP_508627.5
• Gene: sax-1 / 180655
• WormBaseID: WBGene00004727
• Length: 476
• Species: Caenorhabditis elegans
• Alignment Length: 466
• Identity: 135/466 - (28%)
• Similarity: 221/466 - (47%)
• Gaps: 111/466 - (23%)

  Fly   306 KQMAEILSSLGISPDKQQPRRSKYLNQQGGEDNYGASLGADGDGAPGQSFRSCALSVDSLATSTT 370
            |::.|.:|:.|:|.::::.:|..:.:::                            .|.|....|
 Worm    44 KKLEEDISARGLSDEEKEEKRKIHHSKE----------------------------TDYLRLKRT 80

  Fly   371 TMTSGYNSSSCMSLAVTGSGGVGATGETRPGKCSLLDFNFIKVLGKGSFGKVMLAEKKGTDEIYA 435
            .:|                               :.||..:||:|:|:||:|.|.:|..|..|||
 Worm    81 RLT-------------------------------VNDFESLKVIGRGAFGEVRLVQKHDTGHIYA 114

  Fly   436 IKVLKKDAIIQDDDVDCTMTEKRILALAANHPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQK 500
            :|:|:|..:::.:.......|:.||: .|:..::..::..||....|:.|||::.|||:|..:.|
 Worm   115 MKILRKSEMVEKEQTAHVRAERDILS-EADCDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIK 178

  Fly   501 ARRFEASRAAFYAAEVTLALQFLHTHGVIYRDLKLDNILLDQEGHCKLADFGMCKEGIMNGMLTT 565
            ..........||.||..||:||:|:.|.|:||:|.||:|||..||.||:|||:| .|:.....|.
 Worm   179 KDTLTEEATQFYIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGLC-TGLKKFHRTD 242

  Fly   566 TF------------------------------------CGTPDYIAPEILKEQEYGASVDWWALG 594
            .:                                    .|||||||||:.:...|..|.|||:||
 Worm   243 HYRNWPSTLPPDFISKPFESKRKAETWKRNRRAYAYSTVGTPDYIAPEVFQPNGYTKSCDWWSLG 307

  Fly   595 VLMYEMMAGQPPFEADNEDELFDSIMH--DDVLYP--VWLSREAVSILKGFLTKNPEQRLGCTGD 655
            |:||||:.|.|||.::...|.:..:::  ..:::|  |.:|.||.:.:|.|..: .|:|||..|.
 Worm   308 VIMYEMLIGYPPFCSELPQETYRKVINWQQTLVFPSDVPISIEAKATIKRFCCE-AERRLGNHGG 371

  Fly   656 ENEIRKHPFFAKLDWKELEKRNIKPPFRPKMKNPRDANNFDAEFTKEDPVLTPIGNEVVRCINQ- 719
            .:||::.||..::||..:.:|  .||.|..:|:..|.:||| :|..||  ||...:.::|...|
 Worm   372 LDEIKQCPFVKRIDWNHIRER--PPPIRVTVKSIDDTSNFD-DFPDED--LTWPTSTLIRPEEQP 431

  Fly   720 ---DEFAGFSF 727
               .||..|::
 Worm   432 GRRGEFVDFTY 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc98E	NP_524545.2	C2_PKC_epsilon	1..134	CDD:175981
		C1_nPKC_epsilon-like_rpt1	171..230	CDD:410385
		C1_nPKC_epsilon-like_rpt2	250..304	CDD:410388
		STKc_nPKC_epsilon	412..729	CDD:270743	123/360 (34%)
sax-1	NP_508627.5	MobB_NDR-like	18..82	CDD:439270	9/65 (14%)
		STKc_NDR_like	85..443	CDD:270750	125/366 (34%)