Protein Alignment Pkc98E and W04B5.5

DIOPT Version :10

• Sequence 1: NP_524545.2
• Gene: Pkc98E / 43428
• FlyBaseID: FBgn0003093
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: NP_497551.1
• Gene: W04B5.5 / 175360
• WormBaseID: WBGene00021022
• Length: 320
• Species: Caenorhabditis elegans
• Alignment Length: 306
• Identity: 99/306 - (32%)
• Similarity: 156/306 - (50%)
• Gaps: 35/306 - (11%)

  Fly   402 KCSLLDFNFIKVLGKGSFGKVMLAEKK--GTDE--IYAIKVLKKDAIIQDDDVDCTMTEKRILAL 462
            || |.|::..|.:|:|||..|.||.:|  ..||  ..|:|:..|..|:::..|.....||..|||
 Worm    21 KC-LADYSVEKEVGEGSFSTVYLARRKEPKNDENPEVALKICLKRLILKNKMVPYIHREKEALAL 84

  Fly   463 AAN----HPFLTALHSCFQTPDRLFFVMEYVNGGDL--MFQIQKARRFEASRAAFYAAEVTLALQ 521
            .:.    ||.:..|::.||..:.|:||:||...|||  :.|.|...:|..:.:.:|||.:..||:
 Worm    85 ISREENAHPGIVTLYATFQDSESLYFVLEYAKYGDLCTLMQKQPDSKFNVADSRYYAANLLSALE 149

  Fly   522 FLHTHGVIYRDLKLDNILLDQEGHCKLADFGMCK-----EGIMNGML--------TTTFCGTPDY 573
            .:|..|:|:||:|.||:|:..:|...|.|||..|     :.|....:        .::|.||..:
 Worm   150 HIHKLGIIHRDVKADNLLVKSDGRIMLTDFGSSKFLSDYQKIQENPVEEEQPTGRRSSFVGTAFF 214

  Fly   574 IAPEILKEQEYGASVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLYPV---WLSREAV 635
            :.||:|...|...|.|.||..|.:|..:.|..||...:|..:|..|  .|:||..   :....|.
 Worm   215 VTPELLTGSEMSPSSDLWAFSVTLYLFLTGIYPFNDMSEYLVFRRI--QDILYTFSEDFPDENAK 277

  Fly   636 SILKGFLTKNPEQRLGCTGDENEIRKHPFFAKLDWKELEKRNIKPP 681
            ::::..|.|..:.||    ...||::|.||..:|::.||:  ::||
 Worm   278 NLIERLLVKEQKSRL----TSQEIKEHKFFESIDFEHLEQ--LEPP 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc98E	NP_524545.2	C2_PKC_epsilon	1..134	CDD:175981
		C1_nPKC_epsilon-like_rpt1	171..230	CDD:410385
		C1_nPKC_epsilon-like_rpt2	250..304	CDD:410388
		STKc_nPKC_epsilon	412..729	CDD:270743	95/296 (32%)
W04B5.5	NP_497551.1	Protein Kinases, catalytic domain	25..303	CDD:473864	89/283 (31%)