Protein Alignment Pkc98E and rskn-1

DIOPT Version :10

• Sequence 1: NP_524545.2
• Gene: Pkc98E / 43428
• FlyBaseID: FBgn0003093
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: NP_001122504.1
• Gene: rskn-1 / 172647
• WormBaseID: WBGene00011352
• Length: 804
• Species: Caenorhabditis elegans
• Alignment Length: 473
• Identity: 163/473 - (34%)
• Similarity: 238/473 - (50%)
• Gaps: 85/473 - (17%)

  Fly   281 QCETCGMNVHKR-----CQKNVANTCGINTKQMAEILSSLGISPDKQQPRRSKYLNQQGGEDNYG 340
            ||:...|:|..|     |..:..||          ..||:.|.    ||
 Worm    26 QCKDHRMDVSMRSDPTDCSSDTTNT----------FHSSIHII----QP---------------- 60

  Fly   341 ASLGADGDGAPGQSFRSCALSVDSLATSTTTMTSGYNSSSCMSLAVTGSGGVGATGETRPGKCSL 405
                     .|...||......||.:.:...:                 |.|...||    |...
 Worm    61 ---------PPNNGFRLMNWKTDSSSETEIDI-----------------GDVRKCGE----KADP 95

  Fly   406 LDFNFIKVLGKGSFGKVMLAEK-KGTD--EIYAIKVLKKDAIIQDDDVDCTMTEKRILALAANHP 467
            ..|..:||||:||||||.|..| :|.|  .:||:||||| |.::..|...|..|:.||| ..:||
 Worm    96 RQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKK-ATLKVRDRQRTKLERNILA-HISHP 158

  Fly   468 FLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQFLHTHGVIYRD 532
            |:..||..|||..:|:.:::::.||||..::.|...|......||.||:||||:.||:.|::|||
 Worm   159 FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHSLGIVYRD 223

  Fly   533 LKLDNILLDQEGHCKLADFGMCKEGIMNGMLTTTFCGTPDYIAPEILKEQEYGASVDWWALGVLM 597
            ||.:|||||.:||.|:.|||:.||.|.:...|.:||||.:|:|||::..:.:..:.|:|:|||||
 Worm   224 LKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLM 288

  Fly   598 YEMMAGQPPFEADNEDELFDSIMHDDVLYPVWLSREAVSILKGFLTKNPEQRLGCTGD-ENEIRK 661
            :||:.|..||:..:.::....|:...:..|.:|::||.|:|:....:|.:.|||...| ..||::
 Worm   289 FEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKR 353

  Fly   662 HPFFAKLDWKELEKRNIKPPFRPKMKNPRDANNFDAEFTKEDPVLTPI------GNEVVRCINQD 720
            |.||||:|:.:|..:.|.|||:|.:......:.||.||||..|..:|.      |:|:
 Worm   354 HAFFAKIDFVKLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEI------- 411

  Fly   721 EFAGFSFVNPKFGPERKV 738
             |.|||||:.....|||:
 Worm   412 -FRGFSFVSNAVMEERKL 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc98E	NP_524545.2	C2_PKC_epsilon	1..134	CDD:175981
		C1_nPKC_epsilon-like_rpt1	171..230	CDD:410385
		C1_nPKC_epsilon-like_rpt2	250..304	CDD:410388	8/27 (30%)
		STKc_nPKC_epsilon	412..729	CDD:270743	135/326 (41%)
rskn-1	NP_001122504.1	STKc_RSK_N	102..418	CDD:270734	134/325 (41%)
		STKc_RSK_C	447..744	CDD:270993