Protein Alignment Pkc98E and Pkc98E

DIOPT Version :10

• Sequence 1: NP_524545.2
• Gene: Pkc98E / 43428
• FlyBaseID: FBgn0003093
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: XP_061497978.1
• Gene: Pkc98E / 1273220
• VectorBaseID: AGAMI1_006338
• Length: 767
• Species: Anopheles gambiae
• Alignment Length: 794
• Identity: 514/794 - (64%)
• Similarity: 594/794 - (74%)
• Gaps: 85/794 - (10%)

  Fly     1 MFTGKLQIKVCEASGLRPTDFQKRHNLTFGKLADEQLIDPYVSIDVDESHFDRATTRPKTFDPVW 65
            ||||.|::|||||.||||||||.||.:|||:|.| |||||||||||||...||:||:|:||||||
Mosquito     1 MFTGTLRLKVCEAIGLRPTDFQTRHTMTFGRLGD-QLIDPYVSIDVDEKFIDRSTTKPRTFDPVW 64

  Fly    66 NEQFVHDVTNVSNINLTVFHDAALPPDDFVANCIISFEDLM-QSETAVQDLWVNLEPQGKIHVII 129
            ||.|:|:|.|.:.:.:|:||:..: .|.||||..|:|:||: ::|:..||.||:|||||::||.|
Mosquito    65 NESFIHEVENANVLGMTIFHEGPI-TDVFVANTTIAFDDLVTRNESEQQDFWVDLEPQGRLHVKI 128

  Fly   130 ELKNRTDKAKAEAVVEHTVAVNKEFKERAGFNRRRGAMRRRVHQVNGHKFMATFLRQPTFCSHCR 194
            :|:...|   |..|...........|::...||||||||||||||||||||||||||||||||||
Mosquito   129 DLRWTQD---ANNVASQNSCRRAVVKDQPFLNRRRGAMRRRVHQVNGHKFMATFLRQPTFCSHCR 190

  Fly   195 EFIWGIGKQGYQCQVCTLVVHKKCHLSVVSKCPGMRDEQ--PAKVEMVPAGQRFNVNLPHRFVVH 257
            |||||:|||||||||||.||||:||.|||:|||..:|||  |...|   |.||||||:||||.||
Mosquito   191 EFIWGLGKQGYQCQVCTCVVHKRCHSSVVTKCPKKKDEQTKPTPTE---AAQRFNVNMPHRFSVH 252

  Fly   258 SYKRFTFCDHCGSLLYGLIKQGLQCETCGMNVHKRCQKNVANTCGINTKQMAEILSSLGISPDKQ 322
            |:||.||||||||||||:|:|||:||.|.||:|:||:.||||.|||||||:||:|:.:||:.||.
Mosquito   253 SFKRLTFCDHCGSLLYGIIRQGLKCEVCSMNIHRRCEGNVANNCGINTKQLAELLNEMGITMDKT 317

  Fly   323 QPRRSK-------------------------YLNQQGGEDNYGASLGADGDGAPGQSFRSCALSV 362
            .|||||                         |.||. ..||...|..:|...           |:
Mosquito   318 PPRRSKVGEVRCIKMQHSLLMLTYFSFICNQYSNQT-TSDNLSMSERSDDTS-----------SL 370

  Fly   363 DSLATSTTTMTSGYNSSSCMSLAVTGSGGVG-----------ATGET-----------------R 399
            |:|:|.     ||...    .|...|.||.|           |.|.|                 .
Mosquito   371 DTLSTK-----SGAEG----ELGAHGGGGGGGGRGGAGHSSKAGGPTMGMLVNLGTDDDGNARPM 426

  Fly   400 PGKCSLLDFNFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTEKRILALAA 464
            |||..|.||||||||||||||||||||||||||:|||||||||.|:|||||||||||||||||||
Mosquito   427 PGKVFLNDFNFIKVLGKGSFGKVMLAEKKGTDEVYAIKVLKKDVILQDDDVDCTMTEKRILALAA 491

  Fly   465 NHPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQFLHTHGVI 529
            .||||||||||||||||||||||||||||||||||:||:|:..|||||||||||||||||.:|||
Mosquito   492 KHPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQRARKFDEPRAAFYAAEVTLALQFLHRNGVI 556

  Fly   530 YRDLKLDNILLDQEGHCKLADFGMCKEGIMNGMLTTTFCGTPDYIAPEILKEQEYGASVDWWALG 594
            ||||||||||||.||||||||||||||||....||:||||||||||||||:|.:||.||||||||
Mosquito   557 YRDLKLDNILLDAEGHCKLADFGMCKEGITGDNLTSTFCGTPDYIAPEILQELDYGPSVDWWALG 621

  Fly   595 VLMYEMMAGQPPFEADNEDELFDSIMHDDVLYPVWLSREAVSILKGFLTKNPEQRLGCTGDENEI 659
            |||||||||||||||||||:||::|:.||||||||||||||||||||:|||..:|||||..||:|
Mosquito   622 VLMYEMMAGQPPFEADNEDDLFEAILRDDVLYPVWLSREAVSILKGFMTKNAAKRLGCTDGENQI 686

  Fly   660 RKHPFFAKLDWKELEKRNIKPPFRPKMKNPRDANNFDAEFTKEDPVLTPIGNEVVRCINQDEFAG 724
            |.||||..:||:.||:|.::|||||::::.|||.|||.|||||||||||:.|:::||||||||||
Mosquito   687 RSHPFFKDMDWEALEQRKVRPPFRPRVRSARDALNFDTEFTKEDPVLTPVPNDIIRCINQDEFAG 751

  Fly   725 FSFVNPKFGPERKV 738
            |||.||:||||||:
Mosquito   752 FSFTNPEFGPERKI 765

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc98E	NP_524545.2	C2_PKC_epsilon	1..134	CDD:175981	81/133 (61%)
		C1_nPKC_epsilon-like_rpt1	171..230	CDD:410385	52/58 (90%)
		C1_nPKC_epsilon-like_rpt2	250..304	CDD:410388	39/53 (74%)
		STKc_nPKC_epsilon	412..729	CDD:270743	261/316 (83%)
Pkc98E	XP_061497978.1	None