Protein Alignment Pkc98E and RSKR

DIOPT Version :10

• Sequence 1: NP_524545.2
• Gene: Pkc98E / 43428
• FlyBaseID: FBgn0003093
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: NP_001167574.1
• Gene: RSKR / 124923
• HGNCID: 26314
• Length: 410
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 100/311 - (32%)
• Similarity: 157/311 - (50%)
• Gaps: 21/311 - (6%)

  Fly   411 IKVLG---KGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDV-DCTMTEKRILALAANHPFLTA 471
            :|:||   |||||.|:.........::|:||:.|..::|.|.| .|  .|:..:....||||:.:
Human   107 LKILGLVAKGSFGTVLKVLDCTQKAVFAVKVVPKVKVLQRDTVRQC--KEEVSIQRQINHPFVHS 169

  Fly   472 LHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQFLHTHGVIYRDLKLD 536
            |...:|....||.:..|.: .||.........|..:....:|||:.|.|.:||..|:::||:|::
Human   170 LGDSWQGKRHLFIMCSYCS-TDLYSLWSAVGCFPEASIRLFAAELVLVLCYLHDLGIMHRDVKME 233

  Fly   537 NILLDQEGHCKLADFGMCKEGIMNGMLTTTFCGTPDYIAPEILKEQEYGASVDWWALGVLMYEMM 601
            |||||:.||.||.|||:.:. :..|....|.|||..|:|||:|....|..:.|||:||||::.:.
Human   234 NILLDERGHLKLTDFGLSRH-VPQGAQAYTICGTLQYMAPEVLSGGPYNHAADWWSLGVLLFSLA 297

  Fly   602 AGQPPFEADNED-ELFDSIMHDDVLYPVWLSREAVSILKGFLTKNPEQRLGCTGDENEIRKHPFF 665
            .|:.|..|:.:. .:..|:.|.|...|..|::....:|...|.:||..||...   :..:.||||
Human   298 TGKFPVAAERDHVAMLASVTHSDSEIPASLNQGLSLLLHELLCQNPLHRLRYL---HHFQVHPFF 359

  Fly   666 --AKLDWKELEKRNIKPPFRPKMKNPRDA-----NNFDAEFTKEDPVLTPI 709
              ...|.:.|:|:.:......:...|..|     ::||.:.  |..:|.||
Human   360 RGVAFDPELLQKQPVNFVTETQATQPSSAETMPFDDFDCDL--ESFLLYPI 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc98E	NP_524545.2	C2_PKC_epsilon	1..134	CDD:175981
		C1_nPKC_epsilon-like_rpt1	171..230	CDD:410385
		C1_nPKC_epsilon-like_rpt2	250..304	CDD:410388
		STKc_nPKC_epsilon	412..729	CDD:270743	100/310 (32%)
RSKR	NP_001167574.1	STKc_AGC	115..359	CDD:270693	84/250 (34%)