DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pkc98E and LOC101732362

DIOPT Version :9

Sequence 1:	NP_001287577.1	Gene:	Pkc98E / 43428	FlyBaseID:	FBgn0003093	Length:	739	Species:	Drosophila melanogaster
Sequence 2:	XP_004918050.3	Gene:	LOC101732362 / 101732362	-ID:	-	Length:	292	Species:	Xenopus tropicalis

Alignment Length:	281	Identity:	114/281 - (40%)
Similarity:	169/281 - (60%)	Gaps:	19/281 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   456 EKRIL--ALAANHPFLTALHSCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTL 518
            |||||  ..:|.||||.:|::.||:.:.|||||:|:.||||...::....||.|:|.||.|.:.|
Frog    19 EKRILQKVTSAEHPFLVSLYATFQSENHLFFVMKYLPGGDLCHLLEHQGAFEESKAMFYTACIVL 83

  Fly   519 ALQFLHTHGVIYRDLKLDNILLDQEGHCKLADFGMCKEGIMNGMLTTTFCGTPDYIAPEILKEQE 583
            .|:.||.:.:::|||||:|:::|..|:.|:.|||:.|:|...|..:.|.|||..|:||||:.|..
Frog    84 GLEELHRNNIVHRDLKLENLMVDVHGYLKIVDFGLSKDGFRYGDRSKTRCGTNCYMAPEIIDEMA 148

  Fly   584 YGASVDWWALGVLMYEMMAGQPPFEADNEDELFDSIMHDDVLYPVWLSREAVSILKGFLTKNPEQ 648
            |..:||||||||::|.|:..|.||:|:::.|||:||.:|.......||.||..::...|.|||..
Frog   149 YSRAVDWWALGVVLYVMIMFQFPFDAEDDMELFESIRNDKPALTEELSEEAQCLILRLLEKNPCH 213

  Fly   649 RLGCT--GDENEIRKHPFFAKLDWKELEKRNIKPPFRPKMKNPRDANNFDAEFTKEDP-----VL 706
            |||.:  |.| |::.|.||..:||:|..:|...|||:|      |.:.. .|.|::..     ::
Frog   214 RLGSSEAGAE-EVKAHEFFEDIDWEEFLEREQMPPFKP------DVSGL-TESTRQSECQAWGLM 270

  Fly   707 TPIGNEVVRCINQDEFAGFSF 727
            .|.  |.:....|:.|.||.:
Frog   271 PPA--EAISPEAQELFEGFDY 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pkc98E	NP_001287577.1	C2_PKC_epsilon	1..134	CDD:175981
		C1_1	177..228	CDD:278556
		C1_1	252..304	CDD:278556
		STKc_nPKC_epsilon	412..729	CDD:270743	114/281 (41%)
LOC101732362	XP_004918050.3	PKc_like	15..292	CDD:419665	114/281 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910