Protein Alignment Pkc98E and prkcq

DIOPT Version :10

• Sequence 1: NP_524545.2
• Gene: Pkc98E / 43428
• FlyBaseID: FBgn0003093
• Length: 739
• Species: Drosophila melanogaster
• Sequence 2: XP_012813823.2
• Gene: prkcq / 100038268
• XenbaseID: XB-GENE-487643
• Length: 699
• Species: Xenopus tropicalis
• Alignment Length: 648
• Identity: 301/648 - (46%)
• Similarity: 402/648 - (62%)
• Gaps: 59/648 - (9%)

  Fly   108 SETAVQ---------------DLWVNLEPQGKIHVIIELKNRTDKAKAEAVVEHTVAVNKEFKER 157
            |||.|:               ::|:.|:|||:  :|:..:...:::..:   ||....:..|
 Frog    81 SETTVELNSLAERCKKNNGKIEIWIELKPQGR--MIVNARYFLEQSDPK---EHFEDDSSHF--- 137

  Fly   158 AGFNRRRGAMRR-RVHQVNGHKFMATFLRQPTFCSHCREFIWGIGKQGYQCQVCTLVVHKKCHLS 221
             ..::|||||:: :||||..|:|.|||..||||||.|.||:||:.||||||:.|...:||||...
 Frog   138 -ALHQRRGAMKQAKVHQVKCHEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDK 201

  Fly   222 VVSKCPGMRDEQPAKVEMVPAGQRFNVNLPHRFVVHSYKRFTFCDHCGSLLYGLIKQGLQCETCG 286
            |::||.|......   |.|...:||.:::||||.|::|:..|||:|||:||:||.:|||:|..|.
 Frog   202 VIAKCTGSAVNSK---ETVLHKERFKIDMPHRFKVNNYRSPTFCEHCGTLLWGLARQGLKCAECN 263

  Fly   287 MNVHKRCQKNVANTCGINTKQMAEILSSLGISPDKQQPRRSKYLNQQGGEDNYGASLGADGD--- 348
            ||||.:|...|||.||:|.|.|||.|:.:..:...::.|.|:::.:: |..|.|.:......
 Frog   264 MNVHHKCAVKVANLCGVNQKLMAEALAMIETTQQDRRQRDSEFIYRE-GPVNVGPTTNTQDQPIV 327

  Fly   349 -----GAPGQSFRSCALSVDSLATSTTTMTSGYNSSSCMSLAVTGSGGVGATGETRPGKCSLLDF 408
                 .:.|.|:.|...|: .:..|..........||| .:.||.|                 ||
 Frog   328 LSIKKESQGISWESPIESI-KVQESPPEPELKIEQSSC-QIKVTFS-----------------DF 373

  Fly   409 NFIKVLGKGSFGKVMLAEKKGTDEIYAIKVLKKDAIIQDDDVDCTMTEKRILALAANHPFLTALH 473
            ...|:|||||||||.|||.|.|::.:||||||||.::.||||:|||.|||:|:||..|||||.|:
 Frog   374 VLHKMLGKGSFGKVFLAELKRTNQFFAIKVLKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTHLY 438

  Fly   474 SCFQTPDRLFFVMEYVNGGDLMFQIQKARRFEASRAAFYAAEVTLALQFLHTHGVIYRDLKLDNI 538
            ..|||.:.|||||||:|||||||.||...:|:..||.|||||:...|||||:.||:|||||||||
 Frog   439 CTFQTKEHLFFVMEYLNGGDLMFHIQSCHKFDLPRATFYAAEIVCGLQFLHSKGVVYRDLKLDNI 503

  Fly   539 LLDQEGHCKLADFGMCKEGIMNGMLTTTFCGTPDYIAPEILKEQEYGASVDWWALGVLMYEMMAG 603
            |||.|||.|:||||||||.::....|:||||||||||||||..|:|..|||||:.|||:|||:.|
 Frog   504 LLDMEGHIKIADFGMCKESMLGDAKTSTFCGTPDYIAPEILLGQKYNYSVDWWSFGVLLYEMLIG 568

  Fly   604 QPPFEADNEDELFDSIMHDDVLYPVWLSREAVSILKGFLTKNPEQRLGCTGDENEIRKHPFFAKL 668
            |.||...:|:|||.||..|:.:||.:||.||..||.....:.||:|||..||   ||:|.||..:
 Frog   569 QSPFHGIDEEELFQSIRMDNPMYPRFLSMEAKDILIMLFVREPERRLGVKGD---IRQHCFFQHI 630

  Fly   669 DWKELEKRNIKPPFRPKMKNPRDANNFDAEFTKEDPVLTPIGNEVVRCINQDEFAGFSFVNPK 731
            ||..||.|.|:|||:||:|:..|.:|||.||..|.|.|:.....::..::|:.|..|||||||
 Frog   631 DWGRLENREIEPPFKPKVKSADDWSNFDKEFLNEKPRLSSSERTLINSMDQNMFNNFSFVNPK 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pkc98E	NP_524545.2	C2_PKC_epsilon	1..134	CDD:175981	10/40 (25%)
		C1_nPKC_epsilon-like_rpt1	171..230	CDD:410385	35/58 (60%)
		C1_nPKC_epsilon-like_rpt2	250..304	CDD:410388	31/53 (58%)
		STKc_nPKC_epsilon	412..729	CDD:270743	185/316 (59%)
prkcq	XP_012813823.2	C1_nPKC_theta-like_rpt1	150..210	CDD:410384	35/59 (59%)
		C1_nPKC_theta-like_rpt2	229..278	CDD:410387	28/48 (58%)
		STKc_nPKC_theta	367..697	CDD:270770	194/347 (56%)