DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Slu7 and slu7

DIOPT Version :9

Sequence 1:	NP_651659.2	Gene:	Slu7 / 43427	FlyBaseID:	FBgn0039626	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	XP_002944494.2	Gene:	slu7 / 733806	XenbaseID:	XB-GENE-994048	Length:	580	Species:	Xenopus tropicalis

Alignment Length:	599	Identity:	297/599 - (49%)
Similarity:	379/599 - (63%)	Gaps:	88/599 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 EEPKKKSREDWRKAKELEEARKAGTAPAAVDEEGRDINPHIPQYISNAPWYYG-SAGPTLKHQRP 87
            |||||.:||||||.|||||.||.|.|||.|||||:|||||||||||:.|||.. |..||||||||
Frog    20 EEPKKMTREDWRKKKELEEQRKLGNAPAEVDEEGKDINPHIPQYISSVPWYVDPSKRPTLKHQRP 84

  Fly    88 QHEDEQ-----GQLDKRAPKGLNTARIITKFRKGACENCGAVTHKRKDCLERPRKVQAKYAESIV 147
            |.|.::     |...|   ||:....|.||:|:|||:||||:|||:|||.||||:|.||:..:.:
Frog    85 QDEKQKHFTLMGDWYK---KGVMEGSIATKYRQGACDNCGAMTHKKKDCFERPRRVGAKFTGANI 146

  Fly   148 VHDEHLVNEAAVNYDEKRDRWSSYDPANHREIIEEYEKVEEAKRQLKAEKLKND----------- 201
            ..|||...:..::||.|||||:.|:|..|..|:||:.||:.|||.|||:||:.:
Frog   147 APDEHDQPQLMLDYDGKRDRWNGYNPEEHMRIVEEHAKVDLAKRTLKAQKLQEELASGKLSEQVS 211

  Fly   202 --------------PDAEISDEEGNEDKYVDEVDMPGTKVDSKQRITVRNLRIREDTAKYLRNLD 252
                          .:.:.:.|:.:||||.|::||||...|||:||||||||||||||||||||:
Frog   212 SPRHQWGEEEQSSQTERDRNSEDEDEDKYADDIDMPGQNFDSKRRITVRNLRIREDTAKYLRNLN 276

  Fly   253 PNSAYYDPKTRSMRDNP--NPAVPEEEAEFAGENFVRFSGDTTAQATAQLFAWEAHGKGVDVHLL 315
            .||||||||||:||:||  :.....||..:||:||||::|||.:.|..|||||||:.||.||||.
Frog   277 LNSAYYDPKTRAMRENPYSDAGKTPEEVSYAGDNFVRYTGDTISMAQTQLFAWEAYEKGSDVHLQ 341

  Fly   316 AEPTKLELLQKEYEQKKEQFKSSTKTHIVEKYGGEEHLQVPPKSLLLAQTEEYIEYSRSGKVIKG 380
            |:|||||:|.|.::.|||.|:...|..|:|||||:|||.:||..|||||||||:||||.|.||||
Frog   342 ADPTKLEVLAKSFKVKKEDFEHEQKKSILEKYGGQEHLNIPPTELLLAQTEEYVEYSRHGTVIKG 406

  Fly   381 VEKPKARSIYEEDVYINNHTTVWGSFWNAGRWGYKCCKSFIKNSYCVGMQEPEGYSEHHSTSSTA 445
            .||..|:|.||||:.||||..:|||:|..||||||||.||:|.|||.|
Frog   407 QEKAVAKSKYEEDILINNHICIWGSYWKEGRWGYKCCHSFVKMSYCTG----------------- 454

  Fly   446 AATTEPAAQSQFKVPEVPPE--RPTSEVDSASSSEPSSSEEEEVKP--------EKKKTKKKSKK 500
                  .|......|::..|  .||              |||..||        ||.|.|||.||
Frog   455 ------EAGKDINNPDICEEDLMPT--------------EEEMTKPKTLVEIHQEKLKEKKKKKK 499

  Fly   501 REKKKKA---KEQRKQKGKNKETKDKDKTKEKDIPE--ELDDRKRAYNSMYDVKAPTEDEIEEWK 560
            ..|...:   .:::|:|.|.|:..:.::.:.|.:.|  :||:|||.|||:|:.:.|||:|:|.::
Frog   500 HRKSGDSDSDNDEKKKKDKLKKALNAEEARLKQVEEMMQLDERKRGYNSVYESREPTEEEMEAYR 564

  Fly   561 KKRPRAEDPMLQFM 574
            .||.|.:|||..|:
Frog   565 MKRQRPDDPMASFL 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Slu7	NP_651659.2	Slu7	160..405	CDD:371683	150/271 (55%)
slu7	XP_002944494.2	Slu7	158..431	CDD:371683	150/272 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	305	1.000	Domainoid score	I1366
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H4690
Inparanoid	1	1.050	563	1.000	Inparanoid score	I1079
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192250at33208
OrthoFinder	1	1.000	-	-		FOG0003809
OrthoInspector	1	1.000	-	-		oto105423
Panther	1	1.100	-	-	LDO	PTHR12942
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1349
SonicParanoid	1	1.000	-	-		X2654
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.190