DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cpsf100 and SYC1

DIOPT Version :9

Sequence 1:	NP_651658.1	Gene:	Cpsf100 / 43426	FlyBaseID:	FBgn0027873	Length:	756	Species:	Drosophila melanogaster
Sequence 2:	NP_014822.1	Gene:	SYC1 / 854351	SGDID:	S000005705	Length:	188	Species:	Saccharomyces cerevisiae

Alignment Length:	194	Identity:	42/194 - (21%)
Similarity:	63/194 - (32%)	Gaps:	78/194 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   400 TQGEKLNPLIVKPDVEEESSSES---------------EDDIEMSVITGKHDIVVRPEGRHHSGF 449
            |..|....|::..|||.|.|:.|               .|.|.:.:|                |.
Yeast    42 TATENATKLLMLGDVEVEISASSVSIEWTQKSMISQTIADSIVIMII----------------GL 90

  Fly   450 FKSNK----------RHHVMFPYHE-EKVKCDEYGEIINLDDYRIADATGYEFVPMEEQNKENVK 503
            ..|:|          |:|.::...| :.:..:::|     |.:.|.:..|         .|||||
Yeast    91 CASDKNVLSESELKERNHNVWKIQELQNLFREQFG-----DSFSIDEGIG---------KKENVK 141

  Fly   504 KEEPGIGAEQQANGGIVDNDVQLLEKPTKLISQRKTIEVNAQVQRIDFEGRSDGESMLKILSQL 567
            .....||.                .|.|...|..|.|:.|:.    ..:||.  ||:|.|..:|
Yeast   142 NGSVTIGK----------------SKATIDFSTMKLIDCNSN----PLKGRV--ESILSIGQKL 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cpsf100	NP_651658.1	CPSF2-like_MBL-fold	7..204	CDD:293851
		YSH1	19..400	CDD:224157	42/194 (22%)
		Beta-Casp	243..369	CDD:214983
		RMMBL	538..577	CDD:284853	10/30 (33%)
		CPSF100_C	617..753	CDD:290038
SYC1	NP_014822.1	CPSF73-100_C	<28..186	CDD:416974	42/194 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1236
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900