Protein Alignment Cpsf100 and cpsf2

DIOPT Version :10

• Sequence 1: NP_651658.1
• Gene: Cpsf100 / 43426
• FlyBaseID: FBgn0027873
• Length: 756
• Species: Drosophila melanogaster
• Sequence 2: NP_001002384.1
• Gene: cpsf2 / 436657
• ZFINID: ZDB-GENE-040718-79
• Length: 790
• Species: Danio rerio
• Alignment Length: 809
• Identity: 436/809 - (53%)
• Similarity: 565/809 - (69%)
• Gaps: 72/809 - (8%)

  Fly     1 MTSIIKLHTISGAMDESPPCYILQIDDVRILLDCGWDEKFDANFIKELKRQVHTLDAVLLSHPDA 65
            |||||||..:||..:||..||:||:|:.|.||||||||.|..:.|..|||.||.:|||||||||.
Zfish     1 MTSIIKLTALSGVQEESALCYLLQVDEFRFLLDCGWDETFSMDIIDSLKRYVHQVDAVLLSHPDH 65

  Fly    66 YHLGALPYLVGKLGLNCPIYATIPVFKMGQMFMYDLYMSHFNMGDFDLFSLDDVDTAFEKITQLK 130
            .|||||||.||||||||.|||||||:|||||||||||.|..|..||.||:|||||:||:||.|||
Zfish    66 VHLGALPYAVGKLGLNCTIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVDSAFDKIQQLK 130

  Fly   131 YNQTVSLKDKGYGISITPLNAGHMIGGTIWKIVKVGEEDIVYATDFNHKKERHLSGCELDRLQRP 195
            |:|.|:||.||:|:|||||.||||||||||||||.|||:|:|..|||||:|.||:||.|:.|.||
Zfish   131 YSQIVNLKGKGHGLSITPLPAGHMIGGTIWKIVKDGEEEIIYGVDFNHKREIHLNGCSLESLSRP 195

  Fly   196 SLLITDAYNAQYQQARRRARDEKLMTNILQTVRNNGNVLIAVDTAGRVLELAHMLDQLWKNKESG 260
            ||||||::||.|.|.||:.|||:|:||:::|:|.:|||||||||||||||||.:|||:|:.|::|
Zfish   196 SLLITDSFNASYVQPRRKQRDEQLLTNVMETLRGDGNVLIAVDTAGRVLELAQLLDQIWRTKDAG 260

  Fly   261 LMAYSLALLNNVSYNVIEFAKSQIEWMSDKLTKAFEGARNNPFQFKHIQLCHSLADVYKLPAGPK 325
            |..|||||||||||||:||:|||:|||||||.:.||..|||||||:|:.|||||:|:.::|: ||
Zfish   261 LGVYSLALLNNVSYNVVEFSKSQVEWMSDKLMRCFEDKRNNPFQFRHLSLCHSLSDLARVPS-PK 324

  Fly   326 VVLASTPDLESGFTRDLFVQWASNANNSIILTTRTSPGTLAMELVENCAPG-KQIELDVRRRVDL 389
            |||.|.|||||||:|:||:||..:|.||:|||.||:|||||..|::|  || |:|||::|:|..|
Zfish   325 VVLCSQPDLESGFSRELFIQWCQDAKNSVILTYRTTPGTLARYLIDN--PGEKRIELEIRKRCRL 387

  Fly   390 EGAELEEYL---RTQGEKLNPLIVKPDVEEESSSES--EDDIEMSVI--TGKHDIVVRPEGRHHS 447
            ||.|||||:   |.:.|....|....:|:.:||.||  |||:|...:  |..||::::.||....
Zfish   388 EGRELEEYMEKERMKKEAAKKLEQAKEVDLDSSDESDMEDDLEQPAVVKTKHHDLMMKGEGGRKG 452

  Fly   448 GFFKSNKRHHVMFPYHEEKVKCDEYGEIINLDDYRIADATGYEFVPMEEQNKENVKKEEPGIGAE 512
            ||||..|:.:.|||.|||::|.|||||||..:|:         .||..:..:|...|.|.|:
Zfish   453 GFFKQAKKSYSMFPTHEERIKWDEYGEIIRPEDF---------LVPELQATEEEKSKLESGL--- 505

  Fly   513 QQANGGIVDNDVQLLEKPTKLISQRKTIEVNAQVQRIDFEGRSDGESMLKILSQLRPRRVIVIHG 577
               ..|....:..|.:.|||..|..:|:::.|:|..||:||||||:|:.||::|::||::|::||
Zfish   506 ---TNGEEPMEQDLSDVPTKCTSTTQTLDIRARVMYIDYEGRSDGDSIKKIINQMKPRQLIIVHG 567

  Fly   578 TAEGTQVVARHCEQNVG--ARVFTPQKGEIIDVTSEIHIYQVRLTEGLVSQLQFQKGKDAEVAWV 640
            ..:.:|.:|..|:...|  .:|:.|:..|.:|.|||.|||||||.:.|||.|||.|.:|.|:||:
Zfish   568 PPDASQDLAESCKAYSGKDIKVYIPKLQETVDATSETHIYQVRLKDSLVSSLQFCKARDTELAWI 632

  Fly   641 DGRLGMRVKAI-------------------EAPMDVTVEQD--------ASVQEGKTL------- 671
            ||.|.|||:.:                   |..|:||.|.:        |:.:..|||
Zfish   633 DGVLDMRVEKVDTGVIVELGEAKDEAEEGGEQGMEVTEELNTEPSTAAAANQRAMKTLFGEDEKE 697

  Fly   672 ---------TLETLADDEIPIHNSVLINELKLSDFKQTLMRNNINSEFSGGVLWCSNGTLALRRV 727
                     |||.|...|:|.|.||.|||.:||||||.|:|..|.:||.||||.|:| .:|:||.
Zfish   698 ISEESDVIPTLEPLPAHEVPGHQSVFINEPRLSDFKQVLLREGIQAEFVGGVLVCNN-LVAVRRT 761

  Fly   728 DAGKVAMEGCLSEEYYKIRELLYEQYAIV 756
            :||::.:|||..::||:||||||||||:|
Zfish   762 EAGRICLEGCHCDDYYRIRELLYEQYAVV 790

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cpsf100	NP_651658.1	CPSF2-like_MBL-fold	7..204	CDD:293851	138/196 (70%)
		Beta-Casp	243..369	CDD:214983	85/125 (68%)
		RMMBL	539..600	CDD:462191	25/62 (40%)
		CPSF100_C	617..753	CDD:463836	75/178 (42%)
cpsf2	NP_001002384.1	CPSF2-like_MBL-fold	7..204	CDD:293851	138/196 (70%)
		Beta-Casp	243..368	CDD:214983	85/125 (68%)
		PTZ00121	<374..>515	CDD:173412	58/155 (37%)
		RMMBL	529..592	CDD:462191	25/62 (40%)
		CPSF100_C	609..787	CDD:463836	75/178 (42%)