Protein Alignment Cpsf100 and IntS11

DIOPT Version :9

• Sequence 1: NP_651658.1
• Gene: Cpsf100 / 43426
• FlyBaseID: FBgn0027873
• Length: 756
• Species: Drosophila melanogaster
• Sequence 2: NP_651721.1
• Gene: IntS11 / 43506
• FlyBaseID: FBgn0039691
• Length: 597
• Species: Drosophila melanogaster
• Alignment Length: 643
• Identity: 150/643 - (23%)
• Similarity: 254/643 - (39%)
• Gaps: 130/643 - (20%)

  Fly     5 IKLHTISGAMDESPPCYILQIDDVRILLDCGW-----DEKFDANF---IKELKRQVHTLDAVLLS 61
            ||:..:....|....|.:|.:....|:||||.     ||:...:|   :.|.....| :|.|::|
  Fly     4 IKITPLGAGQDVGRSCLLLSMGGKNIMLDCGMHMGYNDERRFPDFSYIVPEGPITSH-IDCVIIS 67

  Fly    62 HPDAYHLGALPYLVGKLGLNCPIYATIPVFKMGQMFMYDL-YMSHFNMGDFDLFSLDDVDTAFEK 125
            |....|.|||||:...:|...|||.|.|...:..:.:.|: .::....|:.:.|:...:....:|
  Fly    68 HFHLDHCGALPYMSEIVGYTGPIYMTHPTKAIAPILLEDMRKVAVERKGESNFFTTQMIKDCMKK 132

  Fly   126 ITQLKYNQTV----SLKDKGYGISITPLNAGHMIGGTI-WKIVKVGEEDIVYATDFNHKKERHLS 185
            :..:..:|::    .|:.|.|       .|||::|..: |  :|||.:.:||..|:|...:|||.
  Fly   133 VIPVTLHQSMMVDTDLEIKAY-------YAGHVLGAAMFW--IKVGSQSVVYTGDYNMTPDRHLG 188

  Fly   186 GCELDRLQRPSLLITDAYNAQYQQARRRARDEKLMTNILQTVRNNGNVLIAVDTAGRVLELAHML 250
            ...:|:. ||.|||:::..|...:..:|.|:...:..:.:.|...|.|||.|...||..||..:|
  Fly   189 AAWIDKC-RPDLLISESTYATTIRDSKRCRERDFLKKVHECVAKGGKVLIPVFALGRAQELCILL 252

  Fly   251 DQLWKNKESGLMAYSLALLNNVSYNVIEFAKSQIEWMSDKLTKAFEGARNNPFQFKHIQLCHSLA 315
            :..|:...   :.|.:.....::.....:.|..|.|.:.|:.|.|  ...|.|.||||:   ...
  Fly   253 ETYWERMN---LKYPIYFALGLTEKANTYYKMFITWTNQKIRKTF--VHRNMFDFKHIK---PFD 309

  Fly   316 DVYKLPAGPKVVLASTPDLESGFTRDLFVQWASNANNSIILTTRTSPGTLA-------------- 366
            ..|....|..||.|:...|.:|.:..:|.:||.|.||.:|:......||:.
  Fly   310 KAYIDNPGAMVVFATPGMLHAGLSLQIFKKWAPNENNMVIMPGYCVQGTVGNKILGGAKKVEFEN 374

  Fly   367 ------------------------MELVENCAP-------GKQIELDVRRRVDLEGAELEEYLRT 400
                                    |:|::||.|       |:..::...|....:...||.|:..
  Fly   375 RQVVEVKMAVEYMSFSAHADAKGIMQLIQNCEPKNVMLVHGEAGKMKFLRSKIKDEFNLETYMPA 439

  Fly   401 QGEKL---NPLIVKPD-------VEEES-SSESEDDIEMSVITGKHDIVVRPEGRHHSGFFKSN- 453
            .||..   .|:.:..|       .|..| :::..|.....:|   |.::|..:.|    ....|
  Fly   440 NGETCVISTPVKIPVDASVSLLKAEARSYNAQPPDPKRRRLI---HGVLVMKDNR----IMLQNL 497

  Fly   454 ---------KRHHVMFPYHEEKVKCDEYGEIINLDDYRIADATGYEFVPMEEQNKENVKKEEPGI 509
                     .||.:.|   ..|||.|:.|.:|.                ..|:.|..::::..|.
  Fly   498 TDALKEIGINRHVMRF---TSKVKMDDSGPVIR----------------TSERLKTLLEEKLAGW 543

  Fly   510 GAEQQANGGIVDNDVQLLEKPTKLISQRKTIEVNAQVQRIDFEGRSDGESMLKILSQL 567
            ....|.||.|....|::..:..:...::|.|.::...|..|.     |..:|.:|..:
  Fly   544 TVTMQENGSIAIESVEVKVEEDEKDPKQKNILISWTNQDEDI-----GAYILNVLQNM 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cpsf100	NP_651658.1	CPSF2-like_MBL-fold	7..204	CDD:293851	58/210 (28%)
		YSH1	19..400	CDD:224157	111/439 (25%)
		Beta-Casp	243..369	CDD:214983	34/163 (21%)
		RMMBL	538..577	CDD:284853	7/30 (23%)
		CPSF100_C	617..753	CDD:290038
IntS11	NP_651721.1	YSH1	4..446	CDD:224157	116/460 (25%)
		INTS11-like_MBL-fold	6..204	CDD:293849	58/208 (28%)
		Beta-Casp	245..363	CDD:214983	33/125 (26%)
		RMMBL	376..416	CDD:284853	5/39 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440177
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1236
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740