Protein Alignment Cpsf100 and Cpsf73

DIOPT Version :10

• Sequence 1: NP_651658.1
• Gene: Cpsf100 / 43426
• FlyBaseID: FBgn0027873
• Length: 756
• Species: Drosophila melanogaster
• Sequence 2: NP_650738.1
• Gene: Cpsf73 / 42240
• FlyBaseID: FBgn0261065
• Length: 684
• Species: Drosophila melanogaster
• Alignment Length: 806
• Identity: 155/806 - (19%)
• Similarity: 295/806 - (36%)
• Gaps: 257/806 - (31%)

  Fly     2 TSIIKLHTISGAMDESPPCYILQIDDVRILLDCGWD---EKFDANFIKELKRQVHTLDAVLLSHP 63
            :.::::..:....:....|.:|:....:|:||||..   ...||....:| .:...:|.:.:||.
  Fly    15 SDLLQIKPLGAGQEVGRSCIMLEFKGKKIMLDCGIHPGLSGMDALPYVDL-IEADEIDLLFISHF 78

  Fly    64 DAYHLGALPYLVGKLGL--NC-PIYATIPVFKMGQMFMYDLYMSHFNMG-DFDLFSLDDVDTAFE 124
            ...|.||||:.:.|...  .| ..:||..:::    :|...|:...|:. :..|::..|::.:.|
  Fly    79 HLDHCGALPWFLMKTSFKGRCFMTHATKAIYR----WMLSDYIKISNISTEQMLYTEADLEASME 139

  Fly   125 KITQLKYNQTVSLKDKGYGISITPLNAGHMIGGTIWKIVKVGEEDIVYATDFNHKKERHLSGCEL 189
            ||..:.:::...:    .|:......|||::|..:: ::::....|:|..||:.:::|||...|:
  Fly   140 KIETINFHEERDV----MGVRFCAYIAGHVLGAAMF-MIEIAGIKILYTGDFSRQEDRHLMAAEV 199

  Fly   190 DRLQRPSLLITDAYNAQYQQARRRARDEKLMTNILQTVRNNGNVLIAVDTAGRVLELAHMLDQLW 254
            ..: :|.:|||::....:...:|..|:.:..:.:.:.|:..|..||.|...||..||..:||:.|
  Fly   200 PPM-KPDVLITESTYGTHIHEKREDRENRFTSLVQKIVQQGGRCLIPVFALGRAQELLLILDEFW 263

  Fly   255 KNKESGLMAYSLALLNNVSYNVIEFAKSQIEWMSDKLTKAFEGARNNPFQFKHIQLCHSLADVYK 319
             ::...|....:...::::...:...::.|..|:|::.:..  |.||||.|:||.....: |.::
  Fly   264 -SQNPDLHEIPIYYASSLAKKCMAVYQTYINAMNDRIRRQI--AVNNPFVFRHISNLKGI-DHFE 324

  Fly   320 LPAGPKVVLASTPDLESGFTRDLFVQWASNANNSIILTTRTSPGTLAMELVENCAPGKQIELDVR 384
             ..||.|::||...::||.:|:||..|.::..|.:|:......||||..::
  Fly   325 -DIGPCVIMASPGMMQSGLSRELFESWCTDPKNGVIIAGYCVEGTLAKAVL-------------- 374

  Fly   385 RRVDLEGAELEEYLRTQGEKLNPLIVKPDVEEESSSESEDDIEMSVITGKHDIVVRPEGRHHSGF 449
                   :|.||.....|:|| ||
  Fly   375 -------SEPEEITTLSGQKL-PL----------------------------------------- 390

  Fly   450 FKSNKRHHVMFPYHEEKVKCDEYGEIINLDDYRIADATGYEFVPMEEQNKENVKKEEPGIGAEQQ 514
                                                                             
  Fly   391 ----------------------------------------------------------------- 390

  Fly   515 ANGGIVDNDVQLLEKPTKLISQRKTIEVNAQVQRIDFEGRSDGESMLKILSQLRPRRVIVIHGTA 579
                                        |..|..|.|...:|.:...:.:..|:|..|:::||
  Fly   391 ----------------------------NMSVDYISFSAHTDYQQTSEFIRLLKPTHVVLVHG-- 425

  Fly   580 EGTQVVARHCEQNVGARV-FTPQKGEIIDVTSEIHIYQVRLTEGLVSQLQFQKGKDAEV------ 637
                      |||..:|: ...|:....|.:::|..|..|.|..:  .|.|:..|.|:|
  Fly   426 ----------EQNEMSRLKLALQREYEADASTDIKFYNPRNTHAV--DLYFRGEKTAKVMGSLAA 478

  Fly   638 --AWVDGRL-GMRVKA-----IEAPMDV---------TVEQDASVQEGKTL-TLETLADD----- 679
              :.|..:| |:.||.     :.||.|:         .|.|..|:..|.:| |||.|.|.
  Fly   479 KNSEVGSKLSGVLVKRDFKYHLLAPSDLGKYTDMSMSVVTQRQSIPWGSSLSTLELLLDRIGAGC 543

  Fly   680 ----------------EIPIHNSVLINELKLSDFKQTLMRNNINSEFSGGVLWCSNGTLALRRVD 728
                            |:.:...:::.|.:.:         ::|..::..||.|      :.:.:
  Fly   544 VEVLEAERKLRVFGCIELTVEQKIIVMEWQAT---------HVNDVYADAVLAC------IMQSE 593

  Fly   729 AGKVAMEGCLSE---EYYKIRELLYE 751
            .|...::|...:   |..:.||.|.|
  Fly   594 LGGTNLKGATKQTKSEDSRFRECLIE 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cpsf100	NP_651658.1	CPSF2-like_MBL-fold	7..204	CDD:293851	47/203 (23%)
		Beta-Casp	243..369	CDD:214983	35/125 (28%)
		RMMBL	539..600	CDD:462191	14/61 (23%)
		CPSF100_C	617..753	CDD:463836	38/183 (21%)
Cpsf73	NP_650738.1	CPSF3-like_MBL-fold	18..211	CDD:293850	47/203 (23%)
		YSH1	19..427	CDD:440849	109/591 (18%)
		CPSF73-100_C	486..680	CDD:463330	30/149 (20%)