Protein Alignment Cpsf100 and IntS9

DIOPT Version :10

• Sequence 1: NP_651658.1
• Gene: Cpsf100 / 43426
• FlyBaseID: FBgn0027873
• Length: 756
• Species: Drosophila melanogaster
• Sequence 2: XP_556128.3
• Gene: IntS9 / 3289982
• VectorBaseID: AGAMI1_005454
• Length: 663
• Species: Anopheles gambiae
• Alignment Length: 730
• Identity: 156/730 - (21%)
• Similarity: 266/730 - (36%)
• Gaps: 238/730 - (32%)

  Fly     5 IKLHTISGAMDESPPCYILQIDDVRILLDCG-------------------------W-----DEK 39
            :||:.:||  |.:.|||:|....:.|:||||                         |     |.:
Mosquito     1 MKLYALSG--DPAKPCYVLSYKGLMIMLDCGLSISSVLNFLPLPLVQSPKFQCLPNWNCRDSDIQ 63

  Fly    40 FDANFIKE----------------LKRQV--HTLDAVLLSHPDAY-HLGALPYLVGKLGLNCPIY 85
            .:...|||                |::.:  ..:|.:|:|:   | ::.||||:....|....:|
Mosquito    64 LEDGEIKECCGCAFVNSAPEFVPPLEKLIDFSEIDVILISN---YTNMLALPYITEGTGFCGEVY 125

  Fly    86 ATIPVFKMGQMFMYDLY-----------------MSH---FNMGDF-------DLFSLDDVDTAF 123
            ||.|..::|:.|:.:|.                 :.|   ..:.|.       .|||:|.|:.:.
Mosquito   126 ATEPTLQIGRFFLEELVEYIEASPKESTARMWKEIQHQLPMPLNDVFKPKNWRHLFSMDAVNKSL 190

  Fly   124 EKITQLKYNQTVSLKDKGYG-ISITPLNAGHMIGGTIWKIVKVGEEDIVYATDFNHKKERHLSGC 187
            .::....|:|.:.:    :| :.:||:::|..:|.:.|.||. |:|.|.|           :||.
Mosquito   191 ARVRMTGYDQKLDI----FGALQVTPISSGFCLGSSNWTIVS-GQEKISY-----------ISGS 239

  Fly   188 E-LDRLQRP----SLLITDAY----NAQYQQARRRARDEKLMTNILQTVRNNGNVLIAVDTAGRV 243
            . |....||    :|..:|..    ..|.......|...:|..|::.|:||.|:|||....:|.|
Mosquito   240 STLTTHPRPINQTALKYSDVVIMTGLTQAPHVNPDAMLGELCMNVMMTLRNGGSVLIPCYPSGVV 304

  Fly   244 LELAHMLDQLWKNKESGLMAYSLALLNNVSYNVIEFAKSQIEWMS-DKLTKAFEGARNNPF---- 303
            .:|...|.....|:  |.....:..::.|:.:.:.::....||:| .|..|.:  ..:.||
Mosquito   305 YDLFECLSVSLDNQ--GFTQIPMFFISPVADSSLAYSNILAEWLSTSKQNKVY--IPDEPFPHAS 365

  Fly   304 --------QFKHIQLCHSLADVYKLPAGPKVVLASTPDLESGFTRDLFVQWASNANNSIILTTRT 360
                    .||||. ....:..::.|.   ||....|.|..|........|.||..::||.|...
Mosquito   366 LVKNAKLKHFKHID-SEGFSTEFRQPC---VVFCGHPSLRFGDAVHFVELWGSNPLHTIIFTEPD 426

  Fly   361 SPGTLAMELVENCAPGKQIELDVRRRVDLEGAELEEYLRTQGEKLNPLI--VKPDVEEESSSESE 423
            .|...|:      ||.:.:      .:......:|..|..|  :.|.||  :||.|
Mosquito   427 FPHMQAL------APYQPL------AIKTVYCPIETSLNFQ--QANKLIKELKPGV--------- 468

  Fly   424 DDIEMSVITGKHDIVVRPEGRHHSGFFKSNKRHHVMFPYHEEKVKCDEYGEIINLDDYRIADATG 488
                          :|.||...........|...|:.|..::.:...:.||:|.|
Mosquito   469 --------------LVIPENYTQPPAIAPQKLDLVIDPIPDKMIIKFKRGEVIKL---------- 509

  Fly   489 YEFVPMEEQ------NKENVK-----KEEPGI------GAEQQANGGIVDNDVQLLE-KPTK--L 533
                |::.:      |.:..|     :.:||:      |..|     :.||...||. :|||  |
Mosquito   510 ----PLKRKRGRVYLNPKMAKTICPQEVQPGVTVSTVTGVLQ-----VKDNIHDLLPLEPTKEEL 565

  Fly   534 ISQRK---------------------TIEVNAQVQRIDFEGRSDGESMLKI-------LSQLRPR 570
            ..:.|                     |:::|..::::..:|.:|    ||:       ::.|.|.
Mosquito   566 ADEHKSKPAGPPQPYSQLRTVRYEWGTLDINLLLKKLAQDGFTD----LKVEQGSADEVTLLLPS 626

  Fly   571 RVIVIHGTAEGTQVV 585
            ...||..:.:.|.:|
Mosquito   627 EDTVIKVSEKSTDIV 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cpsf100	NP_651658.1	CPSF2-like_MBL-fold	7..204	CDD:293851	63/282 (22%)
		Beta-Casp	243..369	CDD:214983	31/138 (22%)
		RMMBL	539..600	CDD:462191	12/54 (22%)
		CPSF100_C	617..753	CDD:463836
IntS9	XP_556128.3	None