Protein Alignment Cpsf100 and dclre1a

DIOPT Version :10

• Sequence 1: NP_651658.1
• Gene: Cpsf100 / 43426
• FlyBaseID: FBgn0027873
• Length: 756
• Species: Drosophila melanogaster
• Sequence 2: NP_001018385.5
• Gene: dclre1a / 324964
• ZFINID: ZDB-GENE-050522-124
• Length: 926
• Species: Danio rerio
• Alignment Length: 828
• Identity: 151/828 - (18%)
• Similarity: 254/828 - (30%)
• Gaps: 281/828 - (33%)

  Fly   129 LKYNQTVSLKDKGYGISITPLNAGHMIGGTIWKIVKVGEEDIVYATDFNHKKERHL------SGC 187
            ||.|:..|.|.:|....:|....    ..|:.|.||..|:.    ||.:|:...:.      ||.
Zfish    16 LKKNKKRSCKSQGSREHVTKRKK----ESTVQKTVKSAEKH----TDLDHQIGSNAPNNTVNSGS 72

  Fly   188 E------LDRLQRPSLLITDAYNAQYQQARRRARDEKLMTNILQTVRNNGNVLIAVDTAGRVLEL 246
            |      :.|         |..||..|..|......::..:||.......:|...:|||.
Zfish    73 EDVNHGTVSR---------DVPNADSQSGRGFCPVCQMPFSILVVQSQQWHVAECLDTAA----- 123

  Fly   247 AHMLDQLWKNKESGLMAYSLALLNNVSYNVIEFAKSQ-----IEWMSDKLTKAFEGARNNPFQFK 306
                |.. |....||...|....:...||....|:|:     ::.:||....:.....:...:..
Zfish   124 ----DNC-KECPDGLQCMSTIPNHYKRYNHSLLAQSRAQNDSVQAISDFSLNSVNNGASTSVKES 183

  Fly   307 HIQLCHSLADVYKLPAGPKVVLASTPD-------LESGFTRDLFVQ--WASNANNS--------- 353
            .:....:::......:.|...|..||.       |.|..|.|:..:  |:.:...|
Zfish   184 SVDSAVNVSASSSQSSSPGDRLKGTPTKSNALLLLRSPNTEDIKKKKGWSPSVKRSQSQISSQEA 248

  Fly   354 ------------IILTTRTSPGTLAMELVE--------NCAPGKQI-ELDVRRRVDLEGAELEEY 397
                        :....:|.|..:..||.|        :|:|..:: |:|...||:....:...|
Zfish   249 KAKISAPGEVRCVDSAVQTQPNEVKKELFECKDDDDYISCSPLSELPEVDEEHRVEKSNNDRHFY 313

  Fly   398 ---LRTQGEKLNPLIVKPDVEEESSSESEDDIEMSVI---------------TGKHDIVVRPEGR 444
               |:...:.||..           |:.:||:...||               ..|....:.||..
Zfish   314 STALQEDDDSLNLF-----------SDEDDDLFFDVIDQYEEHGPDKSSLDTCEKQQTSLAPESH 367

  Fly   445 -----------HHSGFFKSNKRHHVMFPYHEEKVKCDEYGEIINLDDYRIADATGYEFVPMEEQN 498
                       ||.....::....:..|   :.:..:...:.|:...:..:..:.:|.|...:.|
Zfish   368 LTASSSTGVSFHHCSTNNNSSNSQLQSP---QSLVLEHLRDRISTPTHVKSLTSSFEEVNFTQTN 429

  Fly   499 KENVKKE----------------EPGIGAEQQANGGI-----------VDNDVQLLEKPTKLISQ 536
            :|:...:                :.|....:|.:.|:           ...:|:.|.:...|...
Zfish   430 QESFSNQADLSATQSMAPRRTQIKAGPSGLKQTDIGVFFGLKPLHEKKAGKEVKPLVREADLQKS 494

  Fly   537 RKTIEVNAQVQRIDFEGR--------SDG-------ESMLKILSQLRPRRVIVIHGTAEGTQ--- 583
            |:.....||.:....:||        |:|       |..:.:.:|...:|    .|.|||.:
Zfish   495 RRVRVSEAQGEDGKRQGRWRGKSKAPSEGSGVSPAVEDSVALPTQTEGKR----GGRAEGRKRWN 555

  Fly   584 ---------VVARHCE-----QNVGARVFTPQKGEIIDVT------------------SEIHIYQ 616
                     ...:.|.     ...|..|...|.|.:..||                  |.:.||.
Zfish   556 RGKATDGDPKEPKRCPFYKKIPGTGFAVDAFQYGVVEGVTAYFLTHFHSDHYGGLKKDSAVPIYC 620

  Fly   617 VRLTEGLV-SQLQFQKGKDAEVAWVDGRLGMRVKAIEAPMDVTVEQDASVQEGKTLTLETLADDE 680
            .::|..|| |:|:.    |.:...|   |.|..:.|...:.||: .||:...|..:.|..|.|.:
Zfish   621 NKVTSNLVKSKLKV----DEQYIHV---LPMNTECIVQGVKVTL-LDANHCPGAAMLLFVLPDGQ 677

  Fly   681 IPIHNSVLINELKLSDFK----------------QTLMRNN-------------------INSEF 710
            ..:|.         .||:                |||..:.                   :|:.|
Zfish   678 TVLHT---------GDFRADPSMERYPELQGLRIQTLYLDTTYCSPEYTFPTQQEVVTFAVNTAF 733

  Fly   711 SGGVL------WCSNGT---------LALRRVDAGKVAMEGCLSEEYY 743
            ....|      .|  ||         ||:..|.:.||    |||::.|
Zfish   734 ERVTLNPRTLVVC--GTYSVGKEKVFLAVSEVLSSKV----CLSKDKY 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cpsf100	NP_651658.1	CPSF2-like_MBL-fold	7..204	CDD:293851	20/86 (23%)
		Beta-Casp	243..369	CDD:214983	23/160 (14%)
		RMMBL	539..600	CDD:462191	16/92 (17%)
		CPSF100_C	617..753	CDD:463836	39/178 (22%)
dclre1a	NP_001018385.5	None