Protein Alignment Cpsf100 and Dclre1c

DIOPT Version :10

• Sequence 1: NP_651658.1
• Gene: Cpsf100 / 43426
• FlyBaseID: FBgn0027873
• Length: 756
• Species: Drosophila melanogaster
• Sequence 2: NP_671486.2
• Gene: Dclre1c / 259171
• RGDID: 708574
• Length: 698
• Species: Rattus norvegicus
• Alignment Length: 789
• Identity: 143/789 - (18%)
• Similarity: 244/789 - (30%)
• Gaps: 289/789 - (36%)

  Fly     7 LHTISGAMDESPPCYILQIDDVRILLDCGWDEKFDANFIKELKRQVHTLDAVLLSHPDAYHLGAL 71
            :.:..|.|:|.|...|               ::||...:|        ..|..|||....|:..|
  Rat     1 MSSFQGQMEEYPTISI---------------DRFDRENLK--------ARAYFLSHCHKDHMKGL 42

  Fly    72 PYLVGKLGLNCPIYATIPVFKMGQMFMY------DLYMS--HFNMGDFDLFSLDDVDTAFEKITQ 128
            .....|..|.|.:          ::|:|      :|.::  .:...:..:.:::     .|..||
  Rat    43 RAPSMKRRLECSL----------KVFLYCSPVTKELLLTSPKYKFWENRIIAIE-----IETPTQ 92

  Fly   129 LKYNQTVSLKDKGYG----ISITPLNAGHMIGGTIWKIVKVGEEDIVYATDFNHKK------ERH 183
                  |||.|:..|    :.:|.|.|||..|..:: :.:.....::|..||...|      |..
  Rat    93 ------VSLVDEASGEKEEVVVTLLPAGHCPGSVMF-LFQGSNGTVLYTGDFRLAKGEVSRMELL 150

  Fly   184 LSGCELDRLQRPSLLITDAYNAQYQQARRRARDEKLMTNILQTVRN------------------- 229
            .||..:..:|...|..|......||...|    |:.:..:|:.||:
  Rat   151 HSGGRVKDIQSVYLDTTFCDPRFYQIPSR----EECLRGVLELVRSWITRSPKHVVWLNCKAAYG 211

  Fly   230 ----------NGNVLIAVDTAGRVLELAHMLDQL---------------------WKNKESGLMA 263
                      ...|.:.||.......:..:|..|                     |.....|:.:
  Rat   212 YEYLFTNLSEELGVQVHVDKLDMFKNMPDILHHLTTDRNTQIHACRHPKAEEYFQWNKLPCGMAS 276

  Fly   264 YSLALLNNVSYNVIEFAKSQIEWMSDKLTKAFEGARNNPFQFKHIQLCHS--------LADVYKL 320
            .:..:|:.:|      .|....|..::..|.....|.....::.....||        |:.:..:
  Rat   277 KTKTVLHTIS------IKPSTMWFGERTRKTNVIVRTGESSYRACFSFHSSYSEIKDFLSYICPV 335

  Fly   321 PAGPKVV----------------------------------LASTPDLESGFTRDLFVQWASNAN 351
            .|.|.|:                                  .|.|..|:|....|||       :
  Rat   336 NAYPNVIPIGLTVDKVMDFLKPLCRSSQCAEPKYKPLGKLKRARTVHLDSEEDDDLF-------D 393

  Fly   352 NSIILTTR---------------------------TSPGTLAMELVENCAPGKQIELDVRRRVDL 389
            :.::..:|                           .|||....|.:.:.:....::.| ....|.
  Rat   394 DPLLTHSRRKVPYQVTLHPEVFSMKALPLDQPELGQSPGCCKAESMPSPSLANFVDCD-ESNSDS 457

  Fly   390 EGAELEEYLRTQGEKLNPLIV-----KPDVE-----------EESSSESEDDIEMSVITGKHDIV 438
            || |||.....|| .|.|..:     .|||:           :|.:.|..:::..|:.||..
  Rat   458 EG-ELETPPSLQG-GLGPTTLPQQNADPDVDVPRWEVFFKRKDEITDECLENLPSSIETGGS--- 517

  Fly   439 VRPEGRHHSGFFKSNKRHHVMFPYHEEKVKCDEYGEIINLDDYRIADAT--------GYE----- 490
                        :|.||..     ...|:..|..||..::.....:.:|        |::
  Rat   518 ------------QSPKRFS-----DSPKLGSDSDGESTHISSQNSSQSTHITDQGSQGWDSQCDT 565

  Fly   491 -FVPMEEQ--------NKENVK-KEEPGIGA---EQQA----------NGGIVDNDVQLLEKPT- 531
             .:..:|:        ||:..| |.:..|.|   ||.|          ..|...|.|..:|:|.
  Rat   566 VLLSSQEKSGGDSTSLNKDTYKPKPKDSISASQIEQNALCPQDTHCDLKSGAEVNGVPCIEEPDT 630

  Fly   532 ---KLISQRKTIEVNAQV---QRIDFEGRSDGESMLKILSQLRPRRVIVIHG-TAEGTQVVARHC 589
               :..|..||...:.|.   ...|||..|..|:.|.     :|..:..::| .|.|..:|.:
  Rat   631 VSGRKSSPEKTSLTSTQADSQSSSDFEIPSTPEAELP-----KPEHLQFLYGKLATGESIVLK-- 688

  Fly   590 EQNVGARVF 598
            ::||.:::|
  Rat   689 KENVHSQIF 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cpsf100	NP_651658.1	CPSF2-like_MBL-fold	7..204	CDD:293851	44/214 (21%)
		Beta-Casp	243..369	CDD:214983	27/215 (13%)
		RMMBL	539..600	CDD:462191	16/64 (25%)
		CPSF100_C	617..753	CDD:463836
Dclre1c	NP_671486.2	artemis-SNM1C-like_MBL-fold	1..171	CDD:293855	44/214 (21%)
		DRMBL	239..343	CDD:429512	16/109 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	445..485		12/42 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	505..595		17/109 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	620..669		14/53 (26%)