DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cpsf100 and Dclre1b

DIOPT Version :10

Sequence 1:NP_651658.1 Gene:Cpsf100 / 43426 FlyBaseID:FBgn0027873 Length:756 Species:Drosophila melanogaster
Sequence 2:NP_598626.2 Gene:Dclre1b / 140917 MGIID:2156057 Length:541 Species:Mus musculus


Alignment Length:327 Identity:59/327 - (18%)
Similarity:112/327 - (34%) Gaps:77/327 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   144 ISITPLNAGHMIGGTIWKIVKVGEEDIVYATDFNHKKERHLSGCELDRLQRPSLLI--------- 199
            :::|.::|.|..|..:: :.:.....|:|..||.:..         ..|:.|:|::         
Mouse    90 MTVTLIDANHCPGSVMF-LFEGYFGTILYTGDFRYTP---------SMLKEPALILGKQIHTLYL 144

  Fly   200 --TDAYNAQYQQARRRARDEKLMTNILQTVRN--NGNVLIAVDTAGRVLELAHMLDQLWKNKESG 260
              |:...|....:|:.|..:     |:|.:|.  ..|:.|.:.:.|               |||.
Mouse   145 DNTNCNPALVLPSRQEATQQ-----IVQLIRQFPQHNIKIGLYSLG---------------KESL 189

  Fly   261 LMAYSLALLNNVSYNVIEFAKSQIEWMSDKLTKAFEGARNNPFQFKHIQLCHSL--------ADV 317
            |...:|.....|..:.......|:..::|..|...|..|.:...  |.::|||.        ..:
Mouse   190 LEQLALEFRTWVVLSPQRLELVQLLGLADVFTVEEEAGRIHAVD--HTEICHSAMLQWNQSHPTI 252

  Fly   318 YKLPAGPKV-----VLASTPDLESGFTRDLFVQWASNANNSIILTTRTSPGTLAMELVENCAPGK 377
            ...|...||     .:.:.|..:.....:|....|:.....::......|          |....
Mouse   253 AIFPTSRKVRSPHPSIYTVPYSDHSSYSELRAFVAALRPCQVVPIVHQKP----------CGEFF 307

  Fly   378 QIELDVRRRVDLEGAELEEYLRTQGEKLNPL------IVKP---DVEEESSSESEDDIEMSVITG 433
            |..|..|..:.|....:::|:.:...|.|.|      :.:|   .|..||..|..:.:::...:.
Mouse   308 QDSLSPRLAMPLIPHSVQQYMSSSSRKTNVLWQLERRLKRPRTQGVVFESPEEKANQVKVDRDSK 372

  Fly   434 KH 435
            ||
Mouse   373 KH 374

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cpsf100NP_651658.1 CPSF2-like_MBL-fold 7..204 CDD:293851 12/70 (17%)
Beta-Casp 243..369 CDD:214983 22/138 (16%)
RMMBL 539..600 CDD:462191
CPSF100_C 617..753 CDD:463836
Dclre1bNP_598626.2 SNM1A-1C-like_MBL-fold 6..151 CDD:293831 12/70 (17%)
DRMBL 216..298 CDD:429512 14/83 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 455..475
apollo_TRF2_binding 492..524 CDD:212560
TBM 492..507
Blue background indicates that the domain is not in the aligned region.

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