Protein Alignment Cpsf100 and Cpsf73

DIOPT Version :10

• Sequence 1: NP_651658.1
• Gene: Cpsf100 / 43426
• FlyBaseID: FBgn0027873
• Length: 756
• Species: Drosophila melanogaster
• Sequence 2: XP_321933.6
• Gene: Cpsf73 / 1281946
• VectorBaseID: AGAMI1_008254
• Length: 690
• Species: Anopheles gambiae
• Alignment Length: 672
• Identity: 150/672 - (22%)
• Similarity: 279/672 - (41%)
• Gaps: 149/672 - (22%)

  Fly     2 TSIIKLHTISGAMDESPPCYILQIDDVRILLDCG------------WDEKFDANFIKELKRQVHT 54
            :.::.:..:....:....|.:|:....:|:||||            :.:..||:          .
Mosquito    17 SDLMVIRPLGAGQEVGRSCIMLEFKGKKIMLDCGIHPGLSGMDALPFVDLIDAD----------Q 71

  Fly    55 LDAVLLSHPDAYHLGALPYLVGKLGL--NC-PIYATIPVFKMGQMFMYDLYMSHFNMG-DFDLFS 115
            :|.:.:||....|.||||:.:.|...  .| ..:||..:::    :|...|:...|:. |..|::
Mosquito    72 IDLLFISHFHLDHCGALPWFLQKTSFKGRCFMTHATKAIYR----WMLSDYIKVSNISTDQMLYT 132

  Fly   116 LDDVDTAFEKITQLKYNQTVSLKDKGYGISITPLNAGHMIGGTIWKIVKVGEEDIVYATDFNHKK 180
            ..|::.:.|||..:.:::...:    .|:.....||||::|..:: ::::....::|..||:.::
Mosquito   133 EADLEASMEKIETINFHEERDI----LGVRFWAYNAGHVLGAAMF-MIEIAGIRVLYTGDFSRQE 192

  Fly   181 ERHLSGCELDRLQRPSLLITDAYNAQYQQARRRARDEKLMTNILQTVRNNGNVLIAVDTAGRVLE 245
            :|||...|:..: ||.:|||::....:...:|..|:.:..:.:.:.|:..|..||.|...||..|
Mosquito   193 DRHLMAAEIPAM-RPDVLITESTYGTHIHEKREDRENRFTSLVQKIVQQGGRCLIPVFALGRAQE 256

  Fly   246 LAHMLDQLWKNKESGLMAYSLALLNNVSYNVIEFAKSQIEWMSDKLTKAFEGARNNPFQFKHIQL 310
            |..:||:.| ::...|....:...::::...:...::.|..|:||:.:..  |.||||.|:.|..
Mosquito   257 LLLILDEYW-SQNPDLQEIPIYYASSLAKKCMAVYQTYINAMNDKIRRQI--AINNPFVFRFISN 318

  Fly   311 CHSL---ADVYKLPAGPKVVLASTPDLESGFTRDLFVQWASNANNSIILTTRTSPGTLAMELVEN 372
            ...:   .||     ||.||:||...::||.:|:||..|.::..|.:|:......||||..::
Mosquito   319 LKGIDHFDDV-----GPCVVMASPGMMQSGLSRELFESWCTDPKNGVIIAGYCVEGTLAKTIL-- 376

  Fly   373 CAPGKQIELDVRRRVDLEGAELEEYLRTQGEKLNPLIVKPDVEEESSSESEDDIEMSVITGKHDI 437
                               .|.||.....|:|| ||           :.|.|.|..|..|
Mosquito   377 -------------------FEPEEITSMNGQKL-PL-----------NMSVDYISFSAHT----- 405

  Fly   438 VVRPEGRHHSGFFKSNKRHHVMFPYHEEKVKCDEYGEIINLDDYRIADATGYEFVPMEEQNKENV 502
                :.:..|.|.:..:..||:..:.|:    :|.|.:      :.|....||..|..:....|.
Mosquito   406 ----DYQQTSEFIRLLQPTHVVLVHGEQ----NEMGRL------KSALMREYEANPKVQITFHNP 456

  Fly   503 KKEEP-------------------GIGAE-QQANGGIVDNDVQL-LEKPTKLISQR-KTIEVNAQ 545
            :..:|                   |..|: |:.:|.:|..:.:. |..||.|.... .::.:..|
Mosquito   457 RNTQPVELYFRGEKTAKVMGTLAVGEPADCQRLSGVLVKREFKYHLLAPTDLSKYTDMSMSIVTQ 521

  Fly   546 VQRIDFEGRSDGESMLKILSQLR--PRRVIVIHGTAEGTQVVARHCEQNVGARVFTPQKGEIIDV 608
            .|.|.:.|.:   .:||:|.:..  |..|:.. ...||:...||       .||.     :.||:
Mosquito   522 KQSIHWPGST---VVLKLLLERAGGPGSVVET-PIPEGSTATAR-------LRVC-----DCIDL 570

  Fly   609 TSEIHIYQVRLTEGLVSQLQFQ 630
            |:          :|.:..|::|
Mosquito   571 TA----------DGKIVTLEWQ 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cpsf100	NP_651658.1	CPSF2-like_MBL-fold	7..204	CDD:293851	48/212 (23%)
		Beta-Casp	243..369	CDD:214983	37/128 (29%)
		RMMBL	539..600	CDD:462191	15/62 (24%)
		CPSF100_C	617..753	CDD:463836	3/14 (21%)
Cpsf73	XP_321933.6	None