Protein Alignment beta4GalNAcTB and B4GALT4

DIOPT Version :10

• Sequence 1: NP_651657.1
• Gene: beta4GalNAcTB / 43425
• FlyBaseID: FBgn0039625
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_003769.1
• Gene: B4GALT4 / 8702
• HGNCID: 927
• Length: 344
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 104/286 - (36%)
• Similarity: 152/286 - (53%)
• Gaps: 25/286 - (8%)

  Fly    45 KIEGALVPQVTRNVSQQE--VF--ECTYSEIIAENRFVYHLAHYHDAVQRGAEIRPGGEFRPEGC 105
            |:|....|.|:..:..|.  :|  :.|..|:.|||          ..|.|       |.:||:.|
Human    71 KVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAEN----------PKVSR-------GRYRPQEC 118

  Fly   106 QARYSTAIIVPYRQREEQLHAFLTYMHNYLPQQLIHYRIFLVEQFDHKPFNRAMLFNIG-AQVAA 169
            :|....||:||:|.||:.|...|.::|.:|.:|.:.|.|:::.|.:.|.||||.|.|:| .:...
Human   119 KALQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLEALK 183

  Fly   170 EYGFPCLILHDVDLLPLNSGQIYACSERPRHMSSALDHWRFRLPYRGLFGGVVAINTAQYQQING 234
            |..:.|.|.|||||:|.|...:|.|.|.|:|:....:...:||.|.|.||||.|::..|:.::||
Human   184 EENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYRLRYSGYFGGVTALSREQFFKVNG 248

  Fly   235 MSNLYYGWGGEDDDLYERLQALNIDICRFAMEFSKYTMLKH---KQEQPNANRVALLRSATLRQH 296
            .||.|:|||||||||..|::...:.|.|...|..||||:.|   |..:.||.|:.||...:....
Human   249 FSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAERMKLLHQVSRVWR 313

  Fly   297 ADGLNSLVYTEMERRMHSLFTHILVD 322
            .|||:|..|..:....:.|:.:|.||
Human   314 TDGLSSCSYKLVSVEHNPLYINITVD 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
beta4GalNAcTB	NP_651657.1	b4GalT	108..322	CDD:132999	84/217 (39%)
B4GALT4	NP_003769.1	b4GalT	122..339	CDD:132999	84/216 (39%)