DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment beta4GalNAcTB and bre-4

DIOPT Version :9

Sequence 1:	NP_651657.1	Gene:	beta4GalNAcTB / 43425	FlyBaseID:	FBgn0039625	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_490872.1	Gene:	bre-4 / 190668	WormBaseID:	WBGene00000269	Length:	383	Species:	Caenorhabditis elegans

Alignment Length:	230	Identity:	94/230 - (40%)
Similarity:	135/230 - (58%)	Gaps:	4/230 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 GGEFRPEGCQARYSTAIIVPYRQREEQLHAFLTYMHNYLPQQLIHYRIFLVEQFDHKPFNRAMLF 161
            ||...|:.|.||:..|||||||.||..|...|..:|:.|.:|.:.|.||:|||..::.|||..|.
Worm   136 GGHGMPKDCVARHRVAIIVPYRDREAHLRIMLHNLHSLLAKQQLDYAIFIVEQVANQTFNRGKLM 200

  Fly   162 NIGAQVAAE-YGFPCLILHDVDLLPLNSGQIYACSERPRHMSSALDHWRFRLPYRGLFGGVVAIN 225
            |:|..||:. |.:.|.|.|||||||.:...:|.|..:|||||.|:|.:.::|||..:|||:.|:.
Worm   201 NVGYDVASRLYPWQCFIFHDVDLLPEDDRNLYTCPIQPRHMSVAIDKFNYKLPYSAIFGGISALT 265

  Fly   226 TAQYQQINGMSNLYYGWGGEDDDLYERLQALNIDICRFAMEFSKYTMLKHKQEQPN-AN--RVAL 287
            ....::|||.||.::|||||||||..|.....:.:.|:..:.::|.|:||..|..| .|  |..:
Worm   266 KDHLKKINGFSNDFWGWGGEDDDLATRTSMAGLKVSRYPTQIARYKMIKHSTEATNPVNKCRYKI 330

  Fly   288 LRSATLRQHADGLNSLVYTEMERRMHSLFTHILVD 322
            :.....|...|||::|.|..:...:..|:|..:||
Worm   331 MGQTKRRWTRDGLSNLKYKLVNLELKPLYTRAVVD 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
beta4GalNAcTB	NP_651657.1	b4GalT	108..322	CDD:132999	87/217 (40%)
bre-4	NP_490872.1	b4GalT	147..365	CDD:132999	87/217 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3916
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1201618at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19300
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920