DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment beta4GalNAcTB and b4galt2

DIOPT Version :9

Sequence 1:	NP_651657.1	Gene:	beta4GalNAcTB / 43425	FlyBaseID:	FBgn0039625	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_001121857.1	Gene:	b4galt2 / 100148828	ZFINID:	ZDB-GENE-070912-258	Length:	379	Species:	Danio rerio

Alignment Length:	244	Identity:	92/244 - (37%)
Similarity:	143/244 - (58%)	Gaps:	9/244 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 DAVQR-GAEIRPGGEFRPEGCQARYSTAIIVPYRQREEQLHAFLTYMHNYLPQQLIHYRIFLVEQ 149
            :.||| ...:..||::.|..|:.:...|||:|:|.|:..|..:|.|:|..|.:|.|.|.|:::.|
Zfish   127 ERVQRENPNVTEGGKYTPPDCRPKQKVAIIIPFRHRDNHLKYWLHYLHPVLRRQKIDYGIYIINQ 191

  Fly   150 FDHKPFNRAMLFNIGAQVA---AEYGFPCLILHDVDLLPLNSGQIYACSERPRHMSSALDHWRFR 211
            .....||||.|.|:|...|   |||.  |.|..||||:|::...:|.|.::|||.:.|:|.:.||
Zfish   192 LGEDTFNRAKLLNVGYTEAIKDAEYN--CFIFSDVDLIPMDDRNLYHCYDQPRHFAIAMDKFGFR 254

  Fly   212 LPYRGLFGGVVAINTAQYQQINGMSNLYYGWGGEDDDLYERLQALNIDICRFAMEFSKYTMLKH- 275
            |||.|.||||..::..|:.:|||..|.|:||||||||:|.|:....:.:.|..:...:|.|:||
Zfish   255 LPYAGYFGGVSGLSKKQFLKINGFPNEYWGWGGEDDDIYNRITLNGMKVSRPDVRIGRYRMIKHE 319

  Fly   276 --KQEQPNANRVALLRSATLRQHADGLNSLVYTEMERRMHSLFTHILVD 322
              |..:||..|.:.:::.......||::||:|..:..:.:.|:|:|.|:
Zfish   320 RDKHNEPNPQRFSKIQNTKNTMRKDGISSLMYRVVSIKKYPLYTNISVE 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
beta4GalNAcTB	NP_651657.1	b4GalT	108..322	CDD:132999	84/219 (38%)
b4galt2	NP_001121857.1	b4GalT	150..368	CDD:132999	84/219 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3916
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1201618at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19300
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	5	4.880