Protein Alignment eIF4E6 and EIF4E3

DIOPT Version :10

• Sequence 1: NP_651654.1
• Gene: eIF4E6 / 43422
• FlyBaseID: FBgn0039622
• Length: 173
• Species: Drosophila melanogaster
• Sequence 2: XP_047304016.1
• Gene: EIF4E3 / 317649
• HGNCID: 31837
• Length: 256
• Species: Homo sapiens
• Alignment Length: 133
• Identity: 44/133 - (33%)
• Similarity: 67/133 - (50%)
• Gaps: 10/133 - (7%)

  Fly    35 LQNTWTLWGVKYDPEISWEDM---LKEIDSFNTVEDFWNLYFRIDTPSKLNRGCDYMLFKKGIRP 96
            |.::||.|..:..|..:..:.   ||:|.:..||:.||::|..|...:.|...|.|.|.:...||
Human    49 LHSSWTFWLDRSLPGATAAECASNLKKIYTVQTVQIFWSVYNNIPPVTSLPLRCSYHLMRGERRP 113

  Fly    97 MWEDPPNKGGGRWTYKVDKRSTAELDKTWLDVLLCMIGEACDHC----DQICGAFVRIRKNINKI 157
            :||:..|..||.|..||.|.||:.:   |.::||..|||....|    |::.|..|.:|...:.:
Human   114 LWEEESNAKGGVWKMKVPKDSTSTV---WKELLLATIGEQFTDCAAADDEVIGVSVSVRDREDVV 175

  Fly   158 SVW 160
            .||
Human   176 QVW 178

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E6	NP_651654.1	IF4E	35..168	CDD:460281	44/133 (33%)
EIF4E3	XP_047304016.1	IF4E	48..198	CDD:460281	44/133 (33%)