Protein Alignment eIF4E6 and EIF4E

DIOPT Version :9

• Sequence 1: NP_001189306.1
• Gene: eIF4E6 / 43422
• FlyBaseID: FBgn0039622
• Length: 173
• Species: Drosophila melanogaster
• Sequence 2: NP_001124151.1
• Gene: EIF4E / 1977
• HGNCID: 3287
• Length: 248
• Species: Homo sapiens
• Alignment Length: 185
• Identity: 71/185 - (38%)
• Similarity: 94/185 - (50%)
• Gaps: 38/185 - (20%)

  Fly    21 NNKLASLGATNKHRLQNTWTLWGVKYDPEISWEDMLKEIDSFNTVEDFWNLYFRIDTPSKLNRGC 85
            |.::|:.....||.|||.|.||..|.|...:|:..|:.|..|:||||||.||..|...|.|..||
Human    25 NQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGC 89

  Fly    86 DYMLFKKGIRPMWEDPPNKGGGRWTYKVDKRS-TAELDKTWLDV--------------------- 128
            ||.|||.||.|||||..||.||||...::|:. .::||:.||:.
Human    90 DYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETRWDLAMLPRLVSNFWPQVILP 154

  Fly   129 ----------LLCMIGEAC-DHCDQICGAFVRIRKNINKISVWTKADAGDECNEQ 172
                      |||:|||:. |:.|.:|||.|.:|...:||::||     .||..:
Human   155 LQPPKVLELQLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWT-----TECENR 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4E6	NP_001189306.1	IF4E	37..168	CDD:279921	63/163 (39%)
EIF4E	NP_001124151.1	IF4E	38..228	CDD:366742	67/172 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140840
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5053
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54586
OrthoDB	1	1.010	-	-		D1394271at2759
OrthoFinder	1	1.000	-	-		FOG0000666
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11960
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X406
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.820