DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wat and CER4

DIOPT Version :9

Sequence 1:	NP_651652.2	Gene:	wat / 43420	FlyBaseID:	FBgn0039620	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_567936.5	Gene:	CER4 / 829521	AraportID:	AT4G33790	Length:	493	Species:	Arabidopsis thaliana

Alignment Length:	491	Identity:	140/491 - (28%)
Similarity:	228/491 - (46%)	Gaps:	64/491 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 FYKDKGVFLTGGTGFFGKIIIEKLLRVT-EVGQIYLLIRTKKGKDAFARIEDLFNDPVFAK--MK 96
            :..:|.:.:.|..||...|.:||:|||. .|.::|||:|..|||.|..|    |||.:..|  .|
plant    13 YLDNKSILVVGAAGFLANIFVEKILRVAPNVKKLYLLLRASKGKSATQR----FNDEILKKDLFK 73

  Fly    97 QVNPKY--------RCQITIISGDCSLPGLGI-SADERETIMENVNIVLHSAATVRFDEKLKMAI 152
            .:..||        ..:|||:.||..|..||: ..|....::..|:.:::.|||.:|||:..:|:
plant    74 VLKEKYGPNLNQLTSEKITIVDGDICLEDLGLQDFDLAHEMIHQVDAIVNLAATTKFDERYDVAL 138

  Fly   153 AINVHGTKEIIKLAKEIVNLKALVHVSTAFAHCNMRH--IQERFY--SGTMSGENAFKLS----- 208
            .||..|...::..||....:|.|||||||:. |..:.  |.|..|  ..|::|.....::
plant   139 GINTLGALNVLNFAKRCAKVKILVHVSTAYV-CGEKSGLIMETPYRMGETLNGTTGLDINYEKKL 202

  Fly   209 --ECLDEHTL-----NTLTPTI---------IKGYPNTYTFTKVLAENVVQQSAQNLPVTIFRPG 257
              |.||:..:     .|:|.|:         :.|:||||.|||.:.|.:|....:||.:.:.||.
plant   203 VQEKLDQLRVIGAAPETITETMKDLGLRRAKMYGWPNTYVFTKAMGEMMVGTKRENLSLVLLRPS 267

  Fly   258 IVITTYREPVTGWIDNMYGPCGVIVGIGSGVLRVFTGDMDNKAHIVPVDMCVNALLASAWDIARN 322
            |:.:|::||..||.:.:.....:.||.|.|.|..|..|:|..:.::|.||.||::|.|....|..
plant   268 IITSTFKEPFPGWTEGIRTIDSLAVGYGKGKLTCFLCDLDAVSDVMPADMVVNSILVSMAAQAGK 332

  Fly   323 KYETPPIYNYVPDAENMVTWRRYMEDGFEYGCDIPMR----KSIWYPRFTIVPHMWQYHILCFLY 383
            :.|.  ||:......|.:...::.|..:.|....|..    |.:......|:..|..:|    .|
plant   333 QEEI--IYHVGSSLRNPMKNSKFPELAYRYFSIKPWTNKEGKVVKVGAIEILSSMRSFH----RY 391

  Fly   384 HTLPALV----MDAIMVIIGK--KPRMMKIYRKIHKLSNVLKYFSSNEF---RFDNDNVRKLTEK 439
            .|:..|:    ::.:.:|:.|  :.......:||:.:..::..:....|   .||:.|..||.:.
plant   392 MTIRYLIALKGLELVNIILCKLFEKEFQYFNKKINFIFRLVDLYQPYLFFYGIFDDSNTEKLRKM 456

  Fly   440 LDDR--DKRLFAFDMRDLDWTNLF-RVSLYGLRLYV 472
            :...  :..:|.||.:.|||.:.| ...:.||..||
plant   457 VSKTGVENEMFYFDPKVLDWDDYFLNTHVIGLLKYV 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wat	NP_651652.2	PLN02996	35..474	CDD:215538	140/491 (29%)
		FAR-N_SDR_e	39..342	CDD:187547	109/339 (32%)
		FAR_C	382..472	CDD:176924	22/101 (22%)
CER4	NP_567936.5	PLN02996	6..493	CDD:215538	140/491 (29%)
		FAR-N_SDR_e	17..365	CDD:187547	111/354 (31%)
		Sterile	396..493	CDD:281068	22/97 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41718
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815047at2759
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	1	0.900	-	-		OOG6_100550
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.870