DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wat and FAR6

DIOPT Version :9

Sequence 1:	NP_651652.2	Gene:	wat / 43420	FlyBaseID:	FBgn0039620	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001326776.1	Gene:	FAR6 / 824837	AraportID:	AT3G56700	Length:	548	Species:	Arabidopsis thaliana

Alignment Length:	491	Identity:	124/491 - (25%)
Similarity:	221/491 - (45%)	Gaps:	88/491 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 FYKDKGVFLTGGTGFFGKIIIEKLLRVT-EVGQIYLLIRTKKGKDAFARI-EDLFNDPVFAKMKQ 97
            |.:.|...:||.|||..|::||||||.: |:|:|:||:|:|..:.|..|: :::.:..:|..:||
plant    80 FLEGKSYLVTGATGFLAKVLIEKLLRESLEIGKIFLLMRSKDQESANKRLYDEIISSDLFKLLKQ 144

  Fly    98 VN-PKYRC----QITIISGDCSLPGLGISADERETIMENVNIVLHSAATVRFDEKLKMAIAINVH 157
            :: ..|..    ::..:.||.....|||.::....|.|.:::::.......||::...|:::|..
plant   145 MHGSSYEAFMKRKLIPVIGDIEEDNLGIKSEIANMISEEIDVIISCGGRTTFDDRYDSALSVNAL 209

  Fly   158 GTKEIIKLAKEIVNLKALVHVSTAFAHCNMRHIQERFYSGTMSGENAFKLSECLDEHTLNTLTPT 222
            |...::...|....||..:|.|||:.            :|...| ...:...|:.|:..:.|.
plant   210 GPGRLLSFGKGCRKLKLFLHFSTAYV------------TGKREG-TVLETPLCIGENITSDLN-- 259

  Fly   223 IIK---------------------------------GYPNTYTFTKVLAENVVQQSAQNLPVTIF 254
             ||                                 |:.|:|||||.:.|.|:.....||||.|.
plant   260 -IKSELKLASEAVRKFRGREEIKKLKELGFERAQHYGWENSYTFTKAIGEAVIHSKRGNLPVVII 323

  Fly   255 RPGIVITTYREPVTGWIDNMYGPCGVIVGIGSGVLRVFTGDMDNKAHIVPVDMCVNALLASAWDI 319
            ||.|:.::|.||..|||........:|:....|.:..|..|..:...|:||||..||.:|:   :
plant   324 RPSIIESSYNEPFPGWIQGTRMADPIILAYAKGQISDFWADPQSLMDIIPVDMVANAAIAA---M 385

  Fly   320 ARNKYETP--PIYNYVPDAE-NMVTWRRYMEDGFEYGCDIPMRKSIWYPRFTIVPHMWQYHILCF 381
            |::....|  .:||....:. |.:...:.::...::.||.|:.:::     ..:.||       .
plant   386 AKHGCGVPEFKVYNLTSSSHVNPMRAGKLIDLSHQHLCDFPLEETV-----IDLEHM-------K 438

  Fly   382 LYHTLPALVMDAIMVIIGKKPRMM---------KIYRKIHKLSNVLKYFSSNEF---RFDNDNVR 434
            ::.:|.... .|:...|.|:.|::         |..||::...::.|.:....|   ||||.|..
plant   439 IHSSLEGFT-SALSNTIIKQERVIDNEGGGLSTKGKRKLNYFVSLAKTYEPYTFFQARFDNTNTT 502

  Fly   435 KLTEKLDDRDKRLFAFDMRDLDWTN-LFRVSLYGLR 469
            .|.:::...:|:.|.||::.:||.: :..|.|.||:
plant   503 SLIQEMSMEEKKTFGFDIKGIDWEHYIVNVHLPGLK 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wat	NP_651652.2	PLN02996	35..474	CDD:215538	124/491 (25%)
		FAR-N_SDR_e	39..342	CDD:187547	92/345 (27%)
		FAR_C	382..472	CDD:176924	26/101 (26%)
FAR6	NP_001326776.1	PLN02996	77..539	CDD:215538	124/491 (25%)
		FAR-N_SDR_e	84..426	CDD:187547	94/360 (26%)
		FAR_C	<471..539	CDD:176924	21/68 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815047at2759
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	1	0.900	-	-		OOG6_100550
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.870