DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wat and FAR8

DIOPT Version :9

Sequence 1:	NP_651652.2	Gene:	wat / 43420	FlyBaseID:	FBgn0039620	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_190042.2	Gene:	FAR8 / 823581	AraportID:	AT3G44560	Length:	496	Species:	Arabidopsis thaliana

Alignment Length:	500	Identity:	124/500 - (24%)
Similarity:	229/500 - (45%)	Gaps:	72/500 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 FYKDKGVFLTGGTGFFGKIIIEKLLRV-TEVGQIYLLIRTKKGKDAFARIE-DLFNDPVFAKMK- 96
            |.::|.:.:||.|||..|:.:||:||| ..|.::||::|....:.|..|:. :.|...:|..::
plant     8 FLQNKTILVTGATGFLAKVFVEKILRVQPNVNKLYLVVRASDNEAATKRLRTEAFEKDLFKVLRD 72

  Fly    97 -----QVNPKYRCQITIISGDCSLPGLGI-SADERETIMENVNIVLHSAATVRFDEKLKMAIAIN 155
                 ::|.....::..::||.::..||: .::.||.:.:.::||::.|||..|||:..:.:.||
plant    73 NLGDEKLNTLLSEKVVPVAGDIAMDHLGMKDSNLRERMQKEIDIVVNVAATTNFDERYDIGLGIN 137

  Fly   156 VHGTKEIIKLAKEIVNLKALVHVSTAFAHCNMRH--IQER-FYSGTMSGENAFKLSECLDEHTLN 217
            ..|...::..||:.|..:.|:|||||:. |..:.  :.|: |....:..||..:|...|:...:.
plant   138 TFGALNVLNFAKKCVKAQLLLHVSTAYV-CGEKPGLLPEKPFVMEEICNENGLQLDINLERELMK 201

  Fly   218 TLTPTI-----------------------IKGYPNTYTFTKVLAENVVQQSAQNLPVTIFRPGIV 259
            .....:                       :.|:||||.|||.:.|.::....:|||:.|.||.::
plant   202 QRLKELNEQGCSEEGTTFYMKELGMERAKLHGWPNTYVFTKSMGEMLLGNHKENLPLVIIRPTMI 266

  Fly   260 ITTYREPVTGWIDNMYGPCGVIVGIGSGVLRVFTGDMDNKAHIVPVDMCVNALLASAWDIARNKY 324
            .:|..||..|||:.:.....||:..|.|||:.|..|:::...::|.||..||::|:|...|...
plant   267 TSTLFEPFPGWIEGLRTVDSVIIAYGKGVLKCFLVDVNSVCDMIPADMVANAMIAAAATHAGGS- 330

  Fly   325 ETPPIYNYVPDAENMVTWRRYMEDGFEYGCDIPMR----KSIWYPRFTIVPHMWQYHILCFLYHT 385
            :...:|......:|.:.:....|..|.|.....:|    ..|...:..::|.:..:.:...:.:.
plant   331 KVHMVYQVGSSHQNPIIYGEIREILFCYFTKNSLRSRNGSMITVSKMKLIPTLALFSLYMTIRYK 395

  Fly   386 LPALVMDAIMVI---------------IGKKPRMMKIYRKIHKLSNVLKYFSSNEFRFDNDNVRK 435
            ||..::..:.:|               |....|::|:|........:          ||:.|.:.
plant   396 LPVQLLKLVDIIYPSREGDEYKNKNRKIDMVMRLVKLYEPYVLFKGI----------FDDRNTKN 450

  Fly   436 LTEKLDDRDKR-----LFAFDMRDLDWTN-LFRVSLYGLRLYVVK 474
            |..|..:.|.|     :|.||.:.:.|.: |..|.:.||..:|:|
plant   451 LCAKQKEEDNRNSENFMFDFDPKIIKWKDYLINVHIPGLITHVLK 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wat	NP_651652.2	PLN02996	35..474	CDD:215538	123/498 (25%)
		FAR-N_SDR_e	39..342	CDD:187547	93/337 (28%)
		FAR_C	382..472	CDD:176924	22/110 (20%)
FAR8	NP_190042.2	PLN02996	1..495	CDD:215538	123/498 (25%)
		FAR-N_SDR_e	12..362	CDD:187547	96/351 (27%)
		Sterile	394..495	CDD:281068	23/110 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41718
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815047at2759
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	1	0.900	-	-		OOG6_100550
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.870