DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wat and CG1441

DIOPT Version :9

Sequence 1:	NP_651652.2	Gene:	wat / 43420	FlyBaseID:	FBgn0039620	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_610535.1	Gene:	CG1441 / 36029	FlyBaseID:	FBgn0033464	Length:	517	Species:	Drosophila melanogaster

Alignment Length:	488	Identity:	159/488 - (32%)
Similarity:	275/488 - (56%)	Gaps:	12/488 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 YKDKGVFLTGGTGFFGKIIIEKLLR-VTEVGQIYLLIRTKKGKDAFARIEDLFNDPVFAKMKQVN 99
            :|.:.:|:||||||.||:::||||| ...:.:||||||.|||||...||:|:|.:.:|.::||:.
  Fly    32 FKGRSLFITGGTGFLGKVLVEKLLRSCGGLKRIYLLIRPKKGKDPQERIKDIFQNVLFDQVKQMR 96

  Fly   100 PKYRC--QITIISGDCSLPGLGISADERETIMENVNIVLHSAATVRFDEKLKMAIAINVHGTKEI 162
            .:...  |:..|:||...||||||..:.||:.:.|:||.|.||||||||.|:.|:.:|..|||.:
  Fly    97 GEEHILQQVVAIAGDVLSPGLGISEKDLETLRQEVSIVYHCAATVRFDEPLRNAVFMNTRGTKYM 161

  Fly   163 IKLAKEIVNLKALVHVSTAFAHCNMRHIQERFYSGTMSGENAFKLSECLDEHTLNTLTPTIIKGY 227
            ::||..:.:|....:.|||:.|.:::.:.|:.|..........:..|.|.:..:.|:...::...
  Fly   162 LELALTLKHLDFFAYCSTAYCHLHVKTLYEKPYDPPADPHKVMQACEWLTDDEVATIERKVLGAI 226

  Fly   228 PNTYTFTKVLAENVVQQSAQNLPVTIFRPGIVITTYREPVTGWIDNMYGPCGVIVGIGSGVLRVF 292
            ||||.:||.|||.:|.:..:.||..|.||.|||..::||:.||.||:.||.|:::|.|.||:|..
  Fly   227 PNTYAYTKSLAEALVVEKFEELPAVILRPSIVIPIWKEPIPGWTDNINGPTGLLIGAGKGVIRTM 291

  Fly   293 TGDMDNKAHIVPVDMCVNALLASAW-DIARNKYETPPIYNYVPDAENMVTWRRYMEDG-FEYGCD 355
            ..:.......:|||:.||.:|.::| :|.....:|..:.:.....:..|:|...:|.| :.....
  Fly   292 YCNSSGYGDFLPVDVAVNGILVASWRNITAGTDKTNRVAHMTSSNDIKVSWAEIIELGRWVIENK 356

  Fly   356 IPMRKSIWYPRFTIVPHMWQYHILCFLYHTLPALVMDAIMVIIGKKPRMMKIYRKIHKLSNVLKY 420
            :|:....|||..::..:.|.:.|...|:..:|||.:||::.|:...|.:.::..:|:|...|.:|
  Fly   357 VPLNGVAWYPGGSMKSNYWVHFICMVLFQWMPALFVDALLWILRYPPVLCRVQNRIYKGFEVFEY 421

  Fly   421 FSSNEFRFDNDNVRKLTEKLDDRDKRLFAFDMRDLDWTNLFRVSLYGLRLYVVKDDPSNIPESIK 485
            :::|.:.|||....||.:.::::::|.:..:..:||..:.|...:...|..::|:...:||.:.:
  Fly   422 YANNVWNFDNSEAVKLRKLMNNKERRTYVIEKIELDLIDYFTNCVLCARRLILKESDESIPAARR 486

  Fly   486 RYERLKVLH--YTTLAVFYALAAWALYALLKLF 516
            ..:.:.|:.  |..:.:|     ..||.|.:.|
  Fly   487 HMKVMWVVDKVYKGIWIF-----GILYMLYRCF 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wat	NP_651652.2	PLN02996	35..474	CDD:215538	149/442 (34%)
		FAR-N_SDR_e	39..342	CDD:187547	116/306 (38%)
		FAR_C	382..472	CDD:176924	23/89 (26%)
CG1441	NP_610535.1	PLN02996	24..464	CDD:215538	148/431 (34%)
		FAR-N_SDR_e	35..348	CDD:187547	117/312 (38%)
		Sterile	385..475	CDD:281068	22/89 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466778
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I1437
Isobase	1	0.950	-	0.712175	Normalized mean entropy	S3219
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	11	10.850