DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MOS and slpr

DIOPT Version :9

Sequence 1:	NP_005363.1	Gene:	MOS / 4342	HGNCID:	7199	Length:	346	Species:	Homo sapiens
Sequence 2:	NP_001188558.1	Gene:	slpr / 44111	FlyBaseID:	FBgn0030018	Length:	1155	Species:	Drosophila melanogaster

Alignment Length:	342	Identity:	78/342 - (22%)
Similarity:	148/342 - (43%)	Gaps:	86/342 - (25%)

- Green bases have known domain annotations that are detailed below.

Human    27 PSELPAKLLLGATLPRAPRLPRRLAWCSIDWEQVCLLQRLGAGGFGSVYKATYRGVPVAIK---- 87
            |.:|.....:|...|.           .|::.::.:.:.:|:|||..|::..|.|..||||
  Fly   107 PLQLNVSSAIGDIQPH-----------EIEYNELDIKEVIGSGGFCKVHRGYYDGEEVAIKIAHQ 160

Human    88 ----QVNKCTKNRLASRRSFWAELNVARLRHDNI--VRVVAASTRTPAGSNSLGTIIMEFGGNVT 146
                .:.:...|.|...:.|||      |:|:||  :|.|..:|:.        .::||:....:
  Fly   161 TGEDDMQRMRDNVLQEAKLFWA------LKHENIAALRGVCLNTKL--------CLVMEYARGGS 211

Human   147 LHQVIYGAAGHPEGDAGEPHCRTGGQLSLGKCLKYSLDVVNGLLFLHSQ---SIVHLDLKPANIL 208
            |::::                  .|::.....:.:::.:..|:.:||::   ||:|.|||.:|:|
  Fly   212 LNRIL------------------AGKIPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVL 258

Human   209 ISE--------QDVCKISDFGCSEKLEDLLCFQTPSYPLGGTYTHRAPELLKGEGVTPKADIYSF 265
            |.|        |...||:|||.:.::     :.|......|||....||::.....:..:|::|:
  Fly   259 IYEAIEGNHLQQKTLKITDFGLAREM-----YNTQRMSAAGTYAWMPPEVISVSTYSKFSDVWSY 318

Human   266 AITLWQMTTKQAPYSG-ERQHILYAVVAYDLRPSLSAAVFEDSLP-----GQRLGDVIQRCWRPS 324
            .:.||::.|.:.||.| :...:.|.|....|           :||     .:..|.:::.||:..
  Fly   319 GVLLWELITGETPYKGFDPLSVAYGVAVNTL-----------TLPIPKTCPETWGALMKSCWQTD 372

Human   325 AAQRPSARLLLVDLTSL 341
            ..:||..:.:|..|.|:
  Fly   373 PHKRPGFKEILKQLESI 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MOS	NP_005363.1	STKc_Mos	56..338	CDD:270881	71/308 (23%)
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809
		TyrKc	129..386	CDD:197581	71/304 (23%)
		STKc_MLK	134..389	CDD:270963	72/302 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0192
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810